Vol. 14 (2026) | ADMET and DMPK

Vol. 14 (2026)

Published: 06-03-2026

Pharmacology

Neuroprotective cellular and molecular mechanisms of physical exercise on neurodegenerative diseases Review paper

Saswati Swagatika Sahoo, Pratap Kumar Sahu, Nishigandha Sa, Anindita Behera

ADMET and DMPK, Vol. 14 (2026), 3058

Published 11-03-2026;

DOI: https://doi.org/10.5599/admet.3058
- PDF
- HTML
Leveraging network pharmacology in the treatment of asthma Review

Sarthi Ahuja, Richard Cherehani Kashindye, Divya Yadav, Priyanka Chaudhary, Rakesh Yadav

ADMET and DMPK, Vol. 14 (2026), 3281

Published 07-05-2026;

DOI: https://doi.org/10.5599/admet.3281
- PDF
Magnetoreceptive CRY/MagR complexes: linking circadian redox signalling to protein aggregation in Alzheimer’s and Parkinson’s disease Review

Mozhgan Alipour, Behnam Hajipour-Verdom, Faria Ashrafi, Sara Rahmati Roodsari, Shabnam Nohesara, Alireza Zali, Farzad Ashrafi

ADMET and DMPK, Vol. 14 (2026), 3366

Published 28-05-2026;

DOI: https://doi.org/10.5599/admet.3366
- PDF
Anti-amyloid activity of carrageenan-loaded liposomal nanocarriers against subcutaneous insulin-induced amyloid masses in rats Original scientific paper

Saranya Udayakumar, Koyeli Girigoswami, Venkatakrishnan Kiran, Devadass Jessy Mercy, Vijayashree Raghavan, Agnishwar Girigoswami

ADMET and DMPK, Vol. 14 (2026), 3536

Published 20-08-2026;

DOI: https://doi.org/10.5599/admet.3536
- PDF
- Supplementary Material
Precision therapeutics in non-scarring alopecia: a systemic genomic and pathway-based framework for targeted interventions Review paper

Rinky Kapoor, Depti Bellani, Raji Patil, Debalina Bose, Madhuri Pola, Prashant Anilkumar Singh, Mamata Mishra, Debraj Shome

ADMET and DMPK, Vol. 14 (2026), 3030

Published 16-12-2025;

DOI: https://doi.org/10.5599/admet.3030
- PDF
- HTML
Potential effect of nanoformulated iota carrageenan in Aβ1-42 disaggregation: an in vitro, in vivo and in silico study Original scientific article

Saranya Udayakumar, Sanjay Kisan Metkar, Koyeli Girigoswami, Agnishwar Girigoswami

ADMET and DMPK, Vol. 14 (2026), 3122

Published 01-01-2026;

DOI: https://doi.org/10.5599/admet.3122

Pharmaceutics

Structure-activity relationship of captopril derivatives as New Delhi metallo beta-lactamase 1 inhibitors Review paper

Ikhlas Jarrar

ADMET and DMPK, Vol. 14 (2026), 3304

Published 24-05-2026;

DOI: https://doi.org/10.5599/admet.3304
- PDF
- Supplementary Material
Extracellular vesicles and their translational therapeutic potential Original scientific article

Riya Mukherjee, Ramendra Pati Pandey, Chung Ming Chang

ADMET and DMPK, Vol. 14 (2026), 3328

Published 26-07-2026;

DOI: https://doi.org/10.5599/admet.3328
- PDF
- Supplementary Material
From nanoscale to clinic: The growing impact of nanotechnology in translational drug delivery Review paper

Ronny Vargas, Fabiola Martos-Kikut, Noelia Martinez-Martinez, Esteban Lara-Guerrero, Catalina Lizano-Barrantes, Jorge Andrés Pacheco-Molina, Miquel Romero-Obon, Khadija Rouaz-El-Hajoui, Encarna García-Montoya, Pilar Pérez-Lozano, Carlos Suñe, Marc Suñe-Pou

ADMET and DMPK, Vol. 14 (2026), 3495

Published 27-07-2026;

DOI: https://doi.org/10.5599/admet.3495
- PDF
Enhanced anti-inflammatory and antibacterial efficacy of a novel gum ghatti-infused polymeric film for ocular drug delivery Original scientific article

Swagatika Das, Sk Habibullah, Yashwant Giri, Amulyaratna Behera, Gurudutta Pattnaik, Biswaranjan Mohanty

ADMET and DMPK, Vol. 14 (2026), 3200

Published 28-05-2026;

DOI: https://doi.org/10.5599/admet.3200
- PDF
- Supplementary Material
Potential of extracellular vesicles from human Wharton’s jelly and golden berries (Physalis peruviana) combined with polyvinyl alcohol/chitosan/fibroin hydrogel for wound healing: In vitro approaches on 1BR3 cell line Original scientific article

Afrida Rizky Nurfajrin, Indra Wibowo, Anggraini Barlian

ADMET and DMPK, Vol. 14 (2026), 3238

Published 10-04-2026;

DOI: https://doi.org/10.5599/admet.3238
- PDF
- HTML
Mortality prediction with adjuvant tamoxifen in breast cancer: Machine learning-integrated explainable artificial intelligence and Bayesian model results Original scientific article

Kannan Sridharan, Gowri Sivaramakrishnan

ADMET and DMPK, Vol. 14 (2026), 3321

Published 29-04-2026;

DOI: https://doi.org/10.5599/admet.3321
Assessing oxime reactivation efficacy using principal component analysis: Insights from nerve agents inhibited human butyrylcholinesterase Original scientific article

Goran Šinko, Tena Čadež, Zrinka Kovarik, Nikolina Maček Hrvat

ADMET and DMPK, Vol. 14 (2026), 3361

Published 28-05-2026;

DOI: https://doi.org/10.5599/admet.3361
- PDF
- Supplementary Material
Intranasal carvacrol nanoemulsion: Stroke imaging and neuroprotective study Original scientific article

Hitendra Mahajan, Ghanshyam Girnar

ADMET and DMPK, Vol. 14 (2026), 2967

Published 02-12-2025;

DOI: https://doi.org/10.5599/admet.2967
- PDF
- HTML
Liposome-mediated gene delivery: A comprehensive review of biophysical parameters, lipid composition and targeting strategies Review paper

Erfan Jafari Sale, Mohammad Satari, Behnam Hajipour-Verdom

ADMET and DMPK, Vol. 14 (2026), 2065

Published 02-12-2025;

DOI: https://doi.org/10.5599/admet.3065
- PDF
- HTML
Imipramine solubility-pH profiles: self-aggregation vs. common-ion effect Original scientific article

Olivera S. Marković, Miloš P. Pešić, Alex Avdeef, Abu T. M. Serajuddin, Tatjana Verbić

ADMET and DMPK, Vol. 14 (2026), 3128

Published 31-12-2025;

DOI: https://doi.org/10.5599/admet.3128
Novel stirring method for small-scale dissolution test: Rotating vessel method Original scientific article

Shiori Ishida, Samuel Lee, Balint Sinko, Karl Box, Kiyohiko Sugano

ADMET and DMPK, Vol. 14 (2026), 3136

Published 11-01-2026;

DOI: https://doi.org/10.5599/admet.3136
Schiff base metal complexes as emerging therapeutics against antimicrobial-resistant skin pathogens Review paper

Parami Sinhapitiya, Samawansha Tennakoon, Isuri A. D. K. Weeraratne

ADMET and DMPK, Vol. 14 (2026), 3214

Published 06-03-2026;

DOI: https://doi.org/10.5599/admet.3214
- PDF
- HTML
Hypotension and antiphlogistic potential of empagliflozin ocular film: swelling and release kinetics Original scientific paper

Tanisha Das, Subrata Mallick, Sourajit Parida, Mouli Das, Rakesh Swain, Sk Habibullah

ADMET and DMPK, Vol. 14 (2026), 2941

Published 24-11-2025;

DOI: https://doi.org/10.5599/admet.2941
Injectable hydrogels for bone regeneration: mechanical reinforcement strategies using nanoparticles and nanofibers Review paper

Fariba Ganji, Morteza Mirzagoli, Lobat Tayebi

ADMET and DMPK, Vol. 14 (2026), 3037

Published 03-01-2026;

DOI: https://doi.org/10.5599/admet.3037
- PDF
- HTML
Anti-inflammatory potential of plant-derived extracellular vesicles from Solanum nigrum L. integrated in gelatine-dopamine hydrogel on RAW 264.7 and MC3T3 cells Original scientific article

Anggraini Barlian, Tasya Fediarisa, Aida Fitri Kamila, Noviana Vanawati, Yung-Hsin Cheng

ADMET and DMPK, Vol. 14 (2026), 3149

Published 06-03-2026;

DOI: https://doi.org/10.5599/admet.3149
- PDF
- HTML

Pharmacokinetics and toxicology

Bayesian inference for integrated pharmacokinetic modelling of mitragynine and 7-hydroxymitragynine Original scientific article

Dion Notario, Untung Gunawan, Pretty Falena Atmanda Kambira, Erna Wulandari, Eko Adi Prasetyanto

ADMET and DMPK, Vol. 14 (2026), 3170

Published 06-03-2026;

DOI: https://doi.org/10.5599/admet.3170
- PDF
- HTML
Poly(lactic-co-glycolic acid) nanoparticles and microparticles for peptide delivery: release mechanisms and controlling factors Review paper

Mohammadmahdi Eshaghi, Marzieh Dehghani, Azam Abedi, Mehrdad Moosazadeh Moghadam , Ramezan Ali Taheri

ADMET and DMPK, Vol. 14 (2026), 3091

Published 10-12-2025;

DOI: https://doi.org/10.5599/admet.3091
- PDF
- HTML

Medicinal chemistry

High-sensitivity electrochemical immunosensor for anti-SARS-CoV-2 IgG detection using screen-printed carbon/cerium oxide-gold electrode Original scientific aticle

Melania Janisha Devi, Ratu Shifa Syafira, Shabarni Gaffar, Irkham Irkham, Yasuaki Einaga, Yeni Wahyuni Hartati

ADMET and DMPK, Vol. 14 (2026), 3182

Published 10-04-2026;

DOI: https://doi.org/10.5599/admet.3182
Linking biomimetic binding measurements to pharmacokinetic models of volume of distribution and hepatic clearance Review paper

Klara Livia Valko

ADMET and DMPK, Vol. 14 (2026), 3311

Published 29-04-2026;

DOI: https://doi.org/10.5599/admet.3311
- PDF
- HTML
Mechanisms of action of the hexane extract of Hypericum brasiliense and its component uliginosin B against drug-resistant Staphylococcus aureus Original scientific paper

Julia Chaves Scaffo, Sofia Trindade Mussi da Silva, Vitor Won-Held Rabelo, Leandro Stefano Sangenito, Lucas da Silva Abreu, Thaís P. Mello, Leandro Rocha, André Luis Souza dos Santos

ADMET and DMPK, Vol. 14 (2026), 3333

Published 06-07-2026;

DOI: https://doi.org/10.5599/admet.3333
- PDF
Synthesis of NiO nanostructures as electrode materials for the voltammetric determination of epinephrine in the presence of acetaminophen Original scientific article

Mais A. Mohammed, Shemaa A. Soud, Reem Adham Al-Bayati, Shimaa B. Al-Baghdadi

ADMET and DMPK, Vol. 14 (2026), 3201

Published 09-05-2026;

DOI: https://doi.org/10.5599/admet.3201
- PDF
Cholinesterases inhibition profiles with Ugi-derived peptidemimetics: A combined experimental and computational study Original scientific paper

Alma Ramić, Toni Divjak, Lucija Hadrović, Matej Pavlinić, Ana Matošević, Anita Bosak, Jakov Borovec, Bruna Bakota, Tomica Hrenar, Ines Primožič

ADMET and DMPK, Vol. 14 (2026), 3292

Published 23-06-2026;

DOI: https://doi.org/10.5599/admet.3292
- PDF
- Supplementary Material
Inhibition of the mitochondrial fission dynamin-related protein-1 attenuates insulin resistance in hepatoma cells: Implication of mitochondrial dysfunction, apoptosis and nucleolar disruption Original scientific paper

Mai H. Hassan, Thoria Donia , Mohamed Hessien

ADMET and DMPK, Vol. 14 (2026), 3512

Published 20-08-2026;

DOI: https://doi.org/10.5599/admet.3512
- PDF
- Supplementary Material
Plantain peel extract–mediated synthesis of CuO nanoparticles: comprehensive characterization, bioinertness in vitro and in vivo, and anticancer evaluation Original scientific paper

Srimathi JaganMoorthy, Pranav Raaj Subbarayan Ravichandar, Harini Ganesan, Balasubramanian Deepika, Pazhani Durgadevi, Arulsamy Arokyapraveen, Agnishwar Girigoswami, Koyeli Girigoswami

ADMET and DMPK, Vol. 14 (2026), 3203

Published 24-03-2026;

DOI: https://doi.org/10.5599/admet.3203
Design, synthesis and antitubercular evaluation of novel 5,6-diphenyl-1,2,4-triazine-piperazine derivatives targeting mycobacterial dihydrofolate reductase Original scientific article

Uday Thakkar, Moksh Shah, Pratik Khona, Harnisha Patel, Mange Ram Yadav, Salman Patel, Chanchal Singh, Renuka Bhamre, Afzal Nagani

ADMET and DMPK, Vol. 14 (2026), 3322

Published 08-06-2026;

DOI: https://doi.org/10.5599/admet.3322
- PDF
Comprehensive review of biosynthesis, plant function, metabolism and new therapeutic bioactivities of flavonoids Review paper

Iman Permana Maksum, Tati Herlina, Teruna J Siahaan, Yaya Rukayadi, Meiske Naomi Mamuaja

ADMET and DMPK, Vol. 14 (2026), 3404

Published 07-07-2026;

DOI: https://doi.org/10.5599/admet.3404
- PDF
Novel hydroxynaphthalene and quinoline derivatives effective against Trypanosoma and Leishmania Original scientific paper

Tomas Gonec, Tomas Strharsky, Marcela Vettorazzi, Lucas Gutierrez, Martina Cudova, Tereza Kauerova, Michaela Simurdova, Michal Oravec, Jiří Kos, Peter Kollar, Bohuslav Drahos, Jan Jurica, Ondrej Zendulka, Jana Gregorova, Ondrej Pes, Joelle Quetin-Leclercq, Josef Jampilek, Ricardo D. Enriz

ADMET and DMPK, Vol. 14 (2026), 3520

Published 20-08-2026;

DOI: https://doi.org/10.5599/admet.3520
Insights into drug resistance in Leishmania: Mechanisms, therapeutics, and clinical case studies Review paper

Gajala Deethamvali Ghousepeer, Mansi Rani, Aman Kumar, Shubhankar Kumar Singh, Anjali Priyadarshini, Elcio Leal, Shailja Singh, V. Samuel Raj, Subhajit Basu, Ramendra Pati Pandey

ADMET and DMPK, Vol. 14 (2026), 2992

Published 14-01-2026;

DOI: https://doi.org/10.5599/admet.2992
- PDF
- HTML
Anti-infective macrozones: design, biological evaluation and structure-activity relationships Original scientific article

Tomislav Jednačak, Višnja Stepanić, Iva Habinovec, Ivana Mikulandra, Kristina Smokrović, Hana Čipčić Paljetak, Mirjana Bukvić, Jelena Parlov Vuković, Ivan Grgičević, Leda Divjak, Klaus Zangger, Predrag Novak

ADMET and DMPK, Vol. 14 (2026), 3139

Published 14-01-2026;

DOI: https://doi.org/10.5599/admet.3139
Rosanoid diterpenoids: structural diversity, classification and biological activities Review paper

Sabrin R. M. Ibrahim, Hani Z. Asfour , Gamal A. Mohamed, Nabil A. Alhakamy , Hossam M. Abdallah, Hagar M. Mohamed

ADMET and DMPK, Vol. 14 (2026), 3165

Published 06-03-2026;

DOI: https://doi.org/10.5599/admet.3165
- PDF
- HTML

Modelling and simulation

Experimentally derived biomimetic chromatographic descriptors for drug-induced phospholipidosis liability prediction Original scientific paper

Chrysanthos Stergiopoulos, Klara Valko

ADMET and DMPK, Vol. 14 (2026), 3460

Published 10-07-2026;

DOI: https://doi.org/10.5599/admet.3460
- PDF
- Supplementary Material
Prediction of bile salt export pump inhibition using biomimetic chromatographic descriptors: Integrating membrane affinity and protein binding Original scientific article

Chrysanthos Stergiopoulos, Klara Valko

ADMET and DMPK, Vol. 14 (2026), 3303

Published 24-05-2026;

DOI: https://doi.org/10.5599/admet.3303
- PDF
- Supplementary Material
In silico based exploration of natural and synthetic antidiabetic compounds: A comprehensive review of computational approaches Review paper

Ahmad Fariz Maulana, Sriwidodo Sriwidodo, Iman Permana Maksum, Yaya Rukayadi

ADMET and DMPK, Vol. 14 (2026), 3070

Published 06-03-2026;

DOI: https://doi.org/10.5599/admet.3070
- PDF
- HTML

Pharmaceutical and biomedical analysis

Simultaneous quantification of drug and coformer during cocrystal dissolution using in situ UV spectroscopy and multicomponent analysis Original scientific article

Shiori Ishida, Samuel Lee, Balint Sinko, Karl Box, Kiyohiko Sugano

ADMET and DMPK, Vol. 14 (2026), 3274

Published 17-04-2026;

DOI: https://doi.org/10.5599/admet.3274
Engineering affibody-based biosensing platforms for cancer biomarker detection Review paper

Zhafira Fauziah, Robeth Viktoria Manurung, Yuspian Nur, Dika Apriliana Wulandari, Salma Nur Zakiyyah, Irkham Irkham, Yeni Wahyuni Hartati

ADMET and DMPK, Vol. 14 (2026), 3363

Published 11-06-2026;

DOI: https://doi.org/10.5599/admet.3363
- PDF
Electrochemical detection of illicit sibutramine adulteration in herbal weight-loss products using an AgNPs-ErGO modified electrode Original scientific paper

Nguyen Dang Thuy Anh, Vo Thi Cam Le, Huynh Van Chung, Ngo Thi Thanh Xuan, Hoang Thi Minh Nguyet, Pham Thi Thanh Ha, Ha Thuy Trang, Le Hoang Hao, Dao Thi Cam Minh, Nguyen Hai Phong, Dinh Quang Khieu

ADMET and DMPK, Vol. 14 (2026), 3433

Published 05-07-2026;

DOI: https://doi.org/10.5599/admet.3433
- PDF
- Supplementary Material
Simultaneous electrochemical determination of acetaminophen and ciprofloxacin in pharmaceutical formulations using a holmium-modified UiO-66 metal-organic framework electrode Original scientific paper

Nguyen Quang Man, Pham Thi Huyen Thoa, Phan Tu Quy, Truong Thi Phuong Nga, Cao Van Hoang, Le Van Thanh Son, Le Thi Hong Phong, Pham Khac Lieu, Le Lam Son, Dinh Quang Khieu

ADMET and DMPK, Vol. 14 (2026), 3535

Published 15-08-2026;

DOI: https://doi.org/10.5599/admet.3535
- PDF
- Supplementary Material
Titanium dioxide nanoparticle-modified screen-printed electrode for erlotinib determination Original scientific paper

Pooja Das Manjulabhai, Sruthi Mundangadan , Maria Paul, Srinivedha Lal, Namitha Ramalal, Mariya Anto, Dhanya Gangadharan

ADMET and DMPK, Vol. 14 (2026), 3437

Published 09-08-2026;

DOI: https://doi.org/10.5599/admet.3437
- PDF
ZnFe₂O₄ nanoparticle-modified screen-printed electrode for determination of serotonin in the presence of dopamine and tryptophan Original scientific paper

Ahmed Hameed AlSaeedi, Emad Salaam Abood, Rafah Mohammed Thyab

ADMET and DMPK, Vol. 14 (2026), 3504

Published 18-08-2026;

DOI: https://doi.org/10.5599/admet.3504
- PDF
Modelling an alternative lipophilicity scale of bisphenols using biomimetic chromatography: Relevance to membrane-driven baseline toxicity Original scientific paper

Krzesimir Ciura, Julia Nicman, Szymon Zdybel, Giacomo Russo, Lucia Grumetto, Katarzyna Ewa Greber, Anita Sosnowska, Joanna Dołżonek, Karolina Jagiello

ADMET and DMPK, Vol. 14 (2026), 3169

Published 19-03-2026;

DOI: https://doi.org/10.5599/admet.3169
A high-performance voltammetric sensor based on Co/Ni-metal-organic framework modified electrode for the determination of dopamine in the presence of tyrosine Original scientific article

Dhurgham Hani Kadhim Alalwan, Saja Haider Fadhil, Muntaha Mahmood Abed, Noor Kareem Aead, Hussein Ali Qabel

ADMET and DMPK, Vol. 14 (2026), 3246

Published 07-05-2026;

DOI: https://doi.org/10.5599/admet.3246
- PDF
Synthesis and characterization of bimetallic nanocomplex: Application for electrochemical determination of idarubicin as anti-cancer drug Original scientific article

Thekrayat J Joodi Jassim, Raheem Kubaish Barid, Haider Dakhal Hamza

ADMET and DMPK, Vol. 14 (2026), 3342

Published 02-06-2026;

DOI: https://doi.org/10.5599/admet.3342
- PDF
Zn-Ni metal-organic framework nanosheets@graphene oxide nanocomposite: A promising voltammetric platform for sensitive determination of doxorubicin Original scientific paper

Tahereh Kondori, Niloufar Akbarzadeh-T, Somayeh Tajik, Hadi Beitollahi

ADMET and DMPK, Vol. 14 (2026), 3384

Published 08-07-2026;

DOI: https://doi.org/10.5599/admet.3384
- PDF
Graphene-supported Pd/Pt nano-catalysts for enhanced colorimetric detection of dopamine and NADH using paper-based microfluidic devices Original scientific article

Ruri Wahyuono, Jovin Jovin, Ignacius Gilbert Chano, Arda Fridua Putra, Annisa Septyana Ningrum, Muhammad Yusuf Hakim Widianto, Irkham Irkham, Yeni Wahyuni Hartati, Wulan Tri Wahyuni, Isnaini Rahmawati, Chi-Hsien Huang, Yi-Ting Lai

ADMET and DMPK, Vol. 14 (2026), 3247

Published 07-04-2026;

DOI: https://doi.org/10.5599/admet.3247
Bimetallic metal organic framework modified screen printed electrode for simultaneous voltammetric determination of calcium folinate and methotrexate Original scientific paper

Ameer Mahmood Shaker, Batool Nassir Hamran, Ala’a R. Shaker, Hussein Ali Bahrani

ADMET and DMPK, Vol. 14 (2026), 3487

Published 08-08-2026;

DOI: https://doi.org/10.5599/admet.3487
- PDF