Vol. 13 No. 5 (2025) | ADMET and DMPK

Pharmacology

Epithelial-mesenchymal dynamics in cancer: Role of signalling pathways, stromal interactions and natural therapies Review article

Siddharth Singh, Iram Khan, Anindita Behera, Kamesh R Babu, Faisal Rehman, Farah Rehan, Shraddha Manish Gupta

ADMET and DMPK, Vol. 13 No. 5 (2025), 2836

Published 08-09-2025;

DOI: https://doi.org/10.5599/admet.2836
- PDF

Pharmaceutics

Nano-biomaterials in cancer therapy: Advances in targeting and overcoming cancer stem cell resistance Review paper

Marzieh Dehghani, Behnam Hajipour-Verdom, Fatemeh Rahimzadeh, Parviz Abdolmaleki

ADMET and DMPK, Vol. 13 No. 5 (2025), 3007

Published 24-10-2025;

DOI: https://doi.org/10.5599/admet.3007
- PDF
Topical composite hydrogel incorporating human amniotic membrane and spidroin for the treatment of chronic wounds in diabetes mellitus Original scientific article

Suyarta Efrida Pakpahan, Anggraini Barlian, Arie Wibowo, Indra Wibowo

ADMET and DMPK, Vol. 13 No. 5 (2025), 2822

Published 24-08-2025;

DOI: https://doi.org/10.5599/admet.2822
- PDF
Comparison of lipophilic and size-exclusion membranes: creating sink conditions with cyclodextrin Original scientific article

Petra Tőzsér, Szabina Kádár, Edina Szabó, Hajnalka Pataki, Péter Sóti, Péter Laczay, György Tibor Balogh, Bálint Sinkó, Eniko Borbas

ADMET and DMPK, Vol. 13 No. 5 (2025), 2859

Published 27-08-2025;

DOI: https://doi.org/10.5599/admet.2859
- PDF
New xanthone and chemical constituents from the aerial parts of Mallotus glomerulatus and their cytotoxicity in MCF-7 and MDA-MB-231 breast cancer cells Original scientific article

Phongthon Kanjanasirirat, Napasorn Chabang, Chanikarn Wongwitayasombat, Patoomratana Tuchinda, Bamroong Munyoo, Niwat Kangwanrangsan, Suradej Hongeng, Bodee Nutho, Sitthivut Charoensutthivarakul

ADMET and DMPK, Vol. 13 No. 5 (2025), 2901

Published 21-09-2025;

DOI: https://doi.org/10.5599/admet.2901
- PDF
Development of a biorelevant dissolution method for inhalation products: Proof of concept using drugs with diverse solubilities Original scientific article

Amar Elezović, Sandra Cvijić, Saša Pilipović, Alisa Elezović, Jelena Parojčić

ADMET and DMPK, Vol. 13 No. 5 (2025), 2861

Published 04-09-2025;

DOI: https://doi.org/10.5599/admet.2861
- PDF
Advancing through the blood-brain barrier: mechanisms, challenges and drug delivery strategies Review paper

Ronny Vargas, Noelia Martinez-Martinez, Catalina Lizano-Barrantes, Jorge Andrés Pacheco-Molina, Encarna García-Montoya, María Pilar Pérez-Lozano, Josep María Suñe-Negre, Carlos Suñe, Marc Suñe-Pou

ADMET and DMPK, Vol. 13 No. 5 (2025), 2988

Published 19-10-2025;

DOI: https://doi.org/10.5599/admet.2988
- PDF

Pharmacokinetics and toxicology

Elucidating CYP2D6-driven metabolism and hepatotoxic bioactivation of metoprolol in plateable human and animal hepatocytes Original scientific paper

Jiang Pu, Mei Yang, Min Zhang, Ruiqi Gao, Yue Xiao, Lingyu Liu, Chuanjing Zhang, Wennuo Xu, Kaifang Li, Wanyong Feng

ADMET and DMPK, Vol. 13 No. 5 (2025), 2961

Published 30-10-2025;

DOI: https://doi.org/10.5599/admet.2961
- PDF
- Supplementary Material
Pembrolizumab in PD-L1-positive advanced non-small cell lung carcinoma: A meta-analysis of survival benefits and immune-related toxicity events patterns Original scientific article

Alendra Chakramurty, Adetya Rahma Dinni, Ihda Silvia, Aprilyan Laras Cantika, Citrawati Dyah Kencono Wungu

ADMET and DMPK, Vol. 13 No. 5 (2025), 2956

Published 14-10-2025;

DOI: https://doi.org/10.5599/admet.2956
- PDF

Modelling and simulation

Prediction of metabolism and solubility of tablet-form drugs according to the biopharmaceutical drug disposition classification system Original scientific article

Yaroslava Pushkarova, Galina Zaitseva , Kaouthar Bouaalam

ADMET and DMPK, Vol. 13 No. 5 (2025), 2945

Published 17-09-2025;

DOI: https://doi.org/10.5599/admet.2945
- PDF

Pharmaceutical and biomedical analysis

Interaction between albumin originating from persons with uncontrolled diabetes mellitus type 2 and food antioxidants Original scientific article

Miloš Šunderić, Dragana Dekanski, Olgica Nedić

ADMET and DMPK, Vol. 13 No. 5 (2025), 2892

Published 25-09-2025;

DOI: https://doi.org/10.5599/admet.2892
- PDF
- Supplementary Material
Lipid functionalized silver-coated carbon dot-capped manganese ferrite as drug-free core-shell nanoparticles for multimodal imaging and therapy Original scientific article

Anbazhagan Thirumalai, Pazhani Durgadevi, Venkatakrishnan Kiran, Koyeli Girigoswami, Alex Daniel Prabhu, Agnishwar Girigoswami

ADMET and DMPK, Vol. 13 No. 5 (2025), 2905

Published 26-08-2025;

DOI: https://doi.org/10.5599/admet.2905
- PDF

Pharmacology

Epithelial-mesenchymal dynamics in cancer: Role of signalling pathways, stromal interactions and natural therapies Review article

Pharmaceutics

Nano-biomaterials in cancer therapy: Advances in targeting and overcoming cancer stem cell resistance Review paper

Topical composite hydrogel incorporating human amniotic membrane and spidroin for the treatment of chronic wounds in diabetes mellitus Original scientific article

Comparison of lipophilic and size-exclusion membranes: creating sink conditions with cyclodextrin Original scientific article

New xanthone and chemical constituents from the aerial parts of Mallotus glomerulatus and their cytotoxicity in MCF-7 and MDA-MB-231 breast cancer cells Original scientific article

Development of a biorelevant dissolution method for inhalation products: Proof of concept using drugs with diverse solubilities Original scientific article

Advancing through the blood-brain barrier: mechanisms, challenges and drug delivery strategies Review paper

Pharmacokinetics and toxicology

Elucidating CYP2D6-driven metabolism and hepatotoxic bioactivation of metoprolol in plateable human and animal hepatocytes Original scientific paper

Pembrolizumab in PD-L1-positive advanced non-small cell lung carcinoma: A meta-analysis of survival benefits and immune-related toxicity events patterns Original scientific article

Modelling and simulation

Prediction of metabolism and solubility of tablet-form drugs according to the biopharmaceutical drug disposition classification system Original scientific article

Pharmaceutical and biomedical analysis

Interaction between albumin originating from persons with uncontrolled diabetes mellitus type 2 and food antioxidants Original scientific article

Lipid functionalized silver-coated carbon dot-capped manganese ferrite as drug-free core-shell nanoparticles for multimodal imaging and therapy Original scientific article

JIF

elsevier

links

Information