Polyarginine decorated zinc oxide carbon nanotube composite sensor for the voltammetric detection of ferulic acid and hydroquinone
Original scientific paper
DOI:
https://doi.org/10.5599/jese.2711Keywords:
Antioxidant compounds, carbon nanomaterial, metal oxide nanoparticles, Muntingia calabura leaves, thin polymer film, corn samplesAbstract
In the present work, the electrochemical detection of ferulic acid (FA) was done using zinc oxide (ZnO) prepared by the application of the green synthesis method in combination with carbon nanotube modified with arginine (PAG/ZnO-CNTCE). X-ray diffraction, scanning electron microscopy, electrochemical impedance spectroscopy and energy-dispersive X-ray spectroscopy were applied for the morphological and structural analysis of prepared ZnO nanoparticles, ZnO carbon nanotube composite electrode (ZnO-CNTCE), and polyarginine modified electrode, PAG/ZnO-CNTCE. Cyclic voltammetry (CV) and linear sweep voltammetry (LSV) were successfully applied for electrochemical characterization and sensitive detection of FA under optimum conditions of pH, accumulation time, accumulation potential, and scan rate with the transfer of two electrons and two protons. The limit of detection of 0.08 and 0.404 μM, respectively, was obtained for CV and LSV in the wide range of 0.4 to 10.0 μM and 0.2 to 10.0 μM. The limit of quantification was found to be 0.274 and 1.348 μM for CV and LSV. The simultaneous analysis confirmed the selectivity of the electrode towards FA in the presence of hydroquinone at two different potentials. The developed PAG/ZnO-CNTCE exhibited excellent reproducibility, stability, repeatability, and anti-interferent properties. FA was successfully detected at the surface of PAG/ZnO-CNTCE with an impressive recovery rate for both popcorn and corn powder samples.
Downloads
References
[1] D. Yoshihara, N. Fujiwara, K. Suzuki, Antioxidants: Benefits and risks for long-term health, Maturitas 67(2) (2010) 103-107. https://doi.org/10.1016/j.maturitas.2010.05.001 DOI: https://doi.org/10.1016/j.maturitas.2010.05.001
[2] E. de Oliveira Silva, R. Batista, Ferulic Acid and Naturally Occurring Compounds Bearing a Feruloyl Moiety: A Review on Their Structures, Occurrence, and Potential Health Benefits, Comprehensive Reviews in Food Science and Food Safety 16(4) (2017) 580-616. https://doi.org/10.1111/1541-4337.12266 DOI: https://doi.org/10.1111/1541-4337.12266
[3] K. Zduńska, A. Dana, A. Kolodziejczak, H. Rotsztejn, Antioxidant Properties of Ferulic Acid and Its Possible Application, Skin Pharmacology Physiology 31(6) (2018) 332-336. https://doi.org.10.1159/000491755 DOI: https://doi.org/10.1159/000491755
[4] S. S. Damasceno, B. B. Dantas, J. Ribeiro-Filho, Demetrius Antônio M. Araújo, J. Galberto M. da Costa, Chemical Properties of Caffeic and Ferulic Acids in Biological System: Implications in Cancer Therapy. A Review, Current Pharmaceutical Design 23(20) (2017) 3015-3023. http://dx.doi.org/10.2174/1381612822666161208145508 DOI: https://doi.org/10.2174/1381612822666161208145508
[5] E. Girsang, I. N. Ehrich Lister, C. N. Ginting, M. Bethasari, A. Amalia, W. Widowati, Comparison of Antiaging and Antioxidant Activities of Protocatechuic and Ferulic Acids, Molecular and Cellular Biomedical Sciences 4(2) (2020) 68-75. http://dx.doi.org/10.21705/mcbs.v4i2.90 DOI: https://doi.org/10.21705/mcbs.v4i2.90
[6] R. Sauce, C. Aparecida Sales de Oliveira Pinto, M. Valéria Robles Velasco, C. Rosado, A. Rolim Baby, Ex vivo penetration analysis and anti-inflammatory efficacy of the association of ferulic acid and UV filters, European Journal of Pharmaceutical Sciences 156 (2021) 105578. https://doi.org/10.1016/j.ejps.2020.105578 DOI: https://doi.org/10.1016/j.ejps.2020.105578
[7] X.-X. Zhang, D.-S. Zhao, J. Wang, H. Zhou, L. Wang, J.-L. Mao, J.-X. He, The treatment of cardiovascular diseases: a review of ferulic acid and its derivatives, Die Pharmazie - An International Journal of Pharmaceutical Sciences 76(2-3) (2021) 55-60. https://doi.org/10.1691/ph.2021.0958
[8] A. S. Singer Brugiolo, A. C. Carvalho Gouveia, C. C. de Souza Alves, F. M. de Castro e Silva, É. E. de Oliveira, A. P. Ferreira, Ferulic acid supresses Th2 immune response and prevents remodeling in ovalbumin-induced pulmonary allergy associated with inhibition of epithelial-derived cytokines, Pulmonary Pharmacology & Therapeutics 45 (2017) 202-209. https://doi.org/10.1016/j.pupt.2017.07.001 DOI: https://doi.org/10.1016/j.pupt.2017.07.001
[9] I. Antonopoulou, E. Sapountzaki, U. Rova, P. Christakopoulos, Ferulic Acid from Plant Biomass: A Phytochemical with Promising Antiviral Properties, Frontiers in Nutrition 8 (2022) 777576. https://doi.org/10.3389/fnut.2021.777576 DOI: https://doi.org/10.3389/fnut.2021.777576
[10] R. Nankar, P.K. Prabhakar, M. Doble, Hybrid drug combination: Combination of ferulic acid and metformin as anti-diabetic therapy, Phytomedicine 37 (2017) 10-13. https://doi.org/10.1016/j.phymed.2017.10.015 DOI: https://doi.org/10.1016/j.phymed.2017.10.015
[11] C. Shi, X. Zhang, Y. Sun, M. Yang, K. Song, Z. Zheng, Y. Chen, X. Liu, Z. Jia, R. Dong, L. Cui, X. Xia, Antimicrobial Activity of Ferulic Acid Against Cronobacter sakazakii and Possible Mechanism of Action, Foodborne Pathogens and Disease 13(4) (2016). https://doi.org/10.1089/fpd.2015.1992 DOI: https://doi.org/10.1089/fpd.2015.1992
[12] F.-H. Lin, J.-Y. Lin, R. D. Gupta, J. A. Tournas, J. A. Burch, M. A. Selim, N. A. Monteiro-Riviere, J. M. Grichnik, J. Zielinski, S. R. Pinnell, Ferulic Acid Stabilizes a Solution of Vitamins C and E and Doubles its Photoprotection of Skin, Journal of Investigative Dermatology 125(4) (2005) 826-832. https://doi.org/10.1111/j.0022-202X.2005.23768.x DOI: https://doi.org/10.1111/j.0022-202X.2005.23768.x
[13] X. Huang, W. Jiang, J. Zhou, D. G. Yu, H. Liu, The Applications of Ferulic-Acid-Loaded Fibrous Films for Fruit Preservation, Polymers 14(22) (2022) 4947. https://doi.org/10.3390/polym14224947 DOI: https://doi.org/10.3390/polym14224947
[14] N. Kumar, V. Pruthi, Potential applications of ferulic acid from natural sources, Biotechnology Reports 4 (2014) 86-93. https://doi.org/10.1016/j.btre.2014.09.002 DOI: https://doi.org/10.1016/j.btre.2014.09.002
[15] R. Ordoñez, L. Atarés, A. Chiralt, Multilayer antimicrobial films based on starch and PLA with superficially incorporated ferulic or cinnamic acids for active food packaging purposes, Food Chemistry Advances 2 (2023) 100250. https://doi.org/10.1016/j.focha.2023.100250 DOI: https://doi.org/10.1016/j.focha.2023.100250
[16] W. Tian, G. Chen, Y. Gui, G. Zhang, Y. Li, Rapid quantification of total phenolics and ferulic acid in whole wheat using UV-Vis spectrophotometry, Food Control 123 (2021) 107691. https://doi.org/10.1016/j.foodcont.2020.107691 DOI: https://doi.org/10.1016/j.foodcont.2020.107691
[17] X. Chen, J. Mao, F. Wen, X. Xu, Determination of Phenolic Acids in Botanical Pharmaceutical Products by Capillary Electrophoresis with Chemiluminescence Detection, Analytical Letters 54(5) (2020) 817-829. https://doi.org/10.1080/00032719.2020.1783675 DOI: https://doi.org/10.1080/00032719.2020.1783675
[18] L. Fu, Q. Chen, J. Chen, L. Ren, L. Tang, W. Shan, Magnetic carbon nanotubes-molecularly imprinted polymer coupled with HPLC for selective enrichment and determination of ferulic acid in traditional Chinese medicine and biological samples, Journal of Chromatography B 1180 (2021) 122870. https://doi.org/10.1016/j.jchromb.2021.122870 DOI: https://doi.org/10.1016/j.jchromb.2021.122870
[19] S. S. Hingse, S. B. Digole, U. S. Annapure, Method development for simultaneous detection of ferulic acid and vanillin using high-performance thin layer chromatography, Journal of Analytical Science and Technology 5 (2014) 21. https://doi.org/10.1186/s40543-014-0021-6 DOI: https://doi.org/10.1186/s40543-014-0021-6
[20] M. I. Razboršek, M. Ivanović, M. Kolar, Validated Stability-Indicating GC-MS Method for of Forced Degradation Products of Trans-Caffeic Acid and Trans-Ferulic Acid, Molecules 26(9) (2021) 2475. https://doi.org/10.3390/molecules26092475 DOI: https://doi.org/10.3390/molecules26092475
[21] P. Ebrahimi, S. A. Shahidi, M. Bijad, A rapid voltammetric strategy for determination of ferulic acid using electrochemical nanostructure tool in food samples, Journal of Food Measurements and Characterisation 14 (2020) 3389-3396. https://doi.org/10.1007/s11694-020-00585-z DOI: https://doi.org/10.1007/s11694-020-00585-z
[22] T. Zabihpour, S. A. Shahidi, H. Karimi-Maleh, A. Ghorbani-Hasan Saraei, An ultrasensitive electroanalytical sensor based on MgO/SWCNTs- 1-Butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide paste electrode for the determination of ferulic acid in the presence sulfite in food samples, Microchemical Journal 154 (2020) 104572. https://doi.org/10.1016/j.microc.2019.104572 DOI: https://doi.org/10.1016/j.microc.2019.104572
[23] N. Ebrahimi, H. A. Rafiee-Pour, E. Mahmoodi-Khaledi, Ferulic acid detection in honey using carbon paste electrode modified by C-C3N4/Li2CoMn3O8 nanocomposite, Microchemical Journal 203 (2024) 110925. https://doi.org/10.1016/j.microc.2024.110925 DOI: https://doi.org/10.1016/j.microc.2024.110925
[24] S. Rajendrachari, H. Arslanoglu, A. Yaras, S. M. Golabhanvi, Electrochemical Detection of Uric Acid Based on a Carbon Paste Electrode Modified with Ta2O5 Recovered from Ore by a Novel Method, ACS Omega 8(49) (2023) 46946-46954. https://doi.org/10.1021/acsomega.3c06749 DOI: https://doi.org/10.1021/acsomega.3c06749
[25] S. Rajendrachari, N. Basavegowda, R. Vinaykumar, D. Narsimhachary, P. Somu, M. J. Lee, Electrocatalytic determination of methyl orange dye using mechanically alloyed novel metallic glass modified carbon paste electrode by cyclic voltammetry, Inorganic Chemistry Communications 155 (2023) 111010. https://doi.org/10.1016/j.inoche.2023.111010 DOI: https://doi.org/10.1016/j.inoche.2023.111010
[26] R. S. Mahale, V. Rajashekar, S. Vasanth, S. P. Chikkegowda, S. Rajendrachari, V. Mahesh, Fabrication of Mechanically Alloyed Super Duplex Stainless Steel Powder-Modified Carbon Paste Electrode for the Determination of Methylene Blue by the Cyclic Voltammetry Technique, ACS Omega 9(9) (2024) 10660-10670. https://doi.org/10.1021/acsomega.3c09163 DOI: https://doi.org/10.1021/acsomega.3c09163
[27] B. Kanthappa, J. G. Manjunatha, S. A. Aldossari, S. Mohammad, C. Raril, Sensing of paracetamol in the presence of dopamine using an electrochemically polymerized l-alanine layered carbon nanotube sensor, Journal of Materials Science: Materials in Electronics 35 (2024) 768. https://doi.org/10.1007/s10854-024-12535-2 DOI: https://doi.org/10.1007/s10854-024-12535-2
[28] P. Xiao, F. Zhao, B. Zeng, Voltammetric determination of quercetin at a multi-walled carbon nanotube paste electrode, Microchemical Journal 85(2) (2007) 244-249. https://doi.org/10.1016/j.microc.2006.06.004 DOI: https://doi.org/10.1016/j.microc.2006.06.004
[29] P. Kannan, G. Maduraiveeran, Metal Oxides Nanomaterials and Nanocomposite-Based Electrochemical Sensors for Healthcare Applications, Biosensors 13(5) (2023) 542. https://doi.org/10.3390/bios13050542 DOI: https://doi.org/10.3390/bios13050542
[30] S. Devaraj, J. G. Manjunatha, S. A. Aldossari, S. Mohammad, N. Ataollahi, Analysis of Brucine using Poly(L-Arginine) modified biosynthesized CuO nanoparticle composite sensor, Journal of Taibah University for Science 18(1) (2024) 2425082. https://doi.org/10.1080/16583655.2024.2425082 DOI: https://doi.org/10.1080/16583655.2024.2425082
[31] S. Rajendrachari, H. Arslanoglu, A. Yaras, S.M. Golabhanvi, Electrochemical Detection of Uric Acid Based on a Carbon Paste Electrode Modified with Ta2O5 Recovered from Ore by a Novel Method, ACS Omega 8 (49) (2023) 46946-46954. https://doi.org/10.1021/acsomega.3c06749 DOI: https://doi.org/10.1021/acsomega.3c06749
[32] S. Suvetha, G. Muruganandam, G. Hariharan, N. Nesakumar, A. J. Kulandaisamy, J. B. Balaguru Rayappan, B. M. Gunasekaran, Electrochemical investigation on calcium ion sensing and steady-state diffusion analysis using zinc oxide modified glassy carbon electrode, Measurement 221 (2023) 113511. https://doi.org/10.1016/j.measurement.2023.113511 DOI: https://doi.org/10.1016/j.measurement.2023.113511
[33] S. Rajendrachari, P. Taslimi, A. C. Karaoglanli, O. Uzun, E. Alp, G. K. Jayaprakash, Photocatalytic degradation of Rhodamine B (RhB) dye in waste water and enzymatic inhibition study using cauliflower shaped ZnO nanoparticles synthesized by a novel One-pot green synthesis method, Arabian Journal of Chemistry 14(6) (2021) 103180. https://doi.org/10.1016/j.arabjc.2021.103180 DOI: https://doi.org/10.1016/j.arabjc.2021.103180
[34] S. Rajendrachari, E. Altaş, A. Erdogan, Y. Küçük, M. Sabri Gök, F. Khosravi, Electrochemical determination of dopamine by poly (methyl orange) shape memory alloy modified carbon paste electrode, Inorganic Chemistry Communications 167 (2024) 112826. https://doi.org/10.1016/j.inoche.2024.112826 DOI: https://doi.org/10.1016/j.inoche.2024.112826
[35] Y. Yi, Z. Mao, L. Luo, B. Wang, Z. Zhao, Z. Hao, A. Luo, Enhanced performance of microbial electrochemical systems prepared with in situ electropolymerization of L-arginine-modified carbon cloth, Journal of Cleaner Production 392 (2023) 136244. https://doi.org/10.1016/j.jclepro.2023.136244 DOI: https://doi.org/10.1016/j.jclepro.2023.136244
[36] R. Shashanka, Investigation of optical and thermal properties of CuO and ZnO nanoparticles prepared by Crocus Sativus (Saffron) flower extract, Journal of the Iranian Chemical Society 18 (2021) 415-427. https://doi.org/10.1007/s13738-020-02037-3 DOI: https://doi.org/10.1007/s13738-020-02037-3
[37] J. G. Manjunatha, A surfactant enhanced graphene paste electrode as an effective electrochemical sensor for the sensitive and simultaneous determination of catechol and resorcinol, Chemical Data Collection 25 (2020) 100331. https://doi.org/10.1016/j.cdc.2019.100331 DOI: https://doi.org/10.1016/j.cdc.2019.100331
[38] B.M. Amrutha, J.G. Manjunatha, N. Hareesha, A.M. Tighezza, M.D. Albaqami, M. Sillanpää, Electrochemical polymerisation of glutamic acid on the surface of graphene paste electrode for the detection and quantification of rutin in food and medicinal samples, Diagnostics 12 (2022) 3113. https://doi.org/10.3390/diagnostics12123113 DOI: https://doi.org/10.3390/diagnostics12123113
[39] E. Laviron, Theoretical study of a reversible reaction followed by a chemical reaction in thin layer linear potential sweep voltammetry, Journal of Electroanalytical Chemistry and Inter-facial Electrochemistry 39 (1972) 1-23. https://doi.org/10.1016/s0022-0728(72)80472-8 DOI: https://doi.org/10.1016/S0022-0728(72)80472-8
[40] A. V. Bounegru, C. Apetrei, Development of a Novel Electrochemical Biosensor Based on Carbon Nanofibers-Gold Nanoparticles-Tyrosinase for the Detection of Ferulic Acid in Cosmetics, Sensors 20 (2020) 6724. https://doi.org/10.3390/s20236724 DOI: https://doi.org/10.3390/s20236724
[41] S. Battira Madappa, J. G. Manjunatha, M. Karnayana, S. Mahmoud Osman, S. Patra, A surface-modified graphene - carbon-based composite sensor for the voltammetric assessment of pyridoxine in food and pharmaceutical samples, Journal of Taibah University for Science 18(1) (2024) 2359209. https://doi.org/10.1080/16583655.2024.2359209 DOI: https://doi.org/10.1080/16583655.2024.2359209
[42] I. G. David, D. E. Popa, M. Buleandra, S. N. Codreanu, L. Croitoru, L. A. Iordache, H. Noor, Voltammetric Investigation of Ferulic Acid at Disposable Pencil Graphite Electrode, Micromachines 14 (2023) 1951. https://doi.org/10.3390/mi14101951 DOI: https://doi.org/10.3390/mi14101951
[43] A. V. Bounegru, C. Apetrei, Simultaneous Determination of Caffeic Acid and Ferulic Acid Using a Carbon Nanofiber-Based Screen-Printed Sensor, Sensors 22(13) (2022) 4689. https://doi.org/10.3390/s22134689 DOI: https://doi.org/10.3390/s22134689
[44] R. Abdel-Hamid, E. F. Newair, Polypyrrole-Multiwalled Carbon Nanotubes Modified Electrode with Sample Application, Nanomaterials 5(4) (2015) 1704-1715. https://doi.org/10.3390/nano5041704 DOI: https://doi.org/10.3390/nano5041704
[45] G. Ziyatdinova, A. Zhupanova, R. Davletshin, Simultaneous Determination of Ferulic Acid and Vanillin in Vanilla Extracts Using Voltammetric Sensor Based on Electropolymerized Bromocresol Purple, Sensors 22(1) (2022) 288. https://doi.org/10.3390/s22010288 DOI: https://doi.org/10.3390/s22010288
[46] L. Mǎgeruşan, F. Pogǎcean, M. L. Soran, Stela-Maria Pruneanu, Graphene-Based Electrochemical Sensing Platform for Rapid and Selective Ferulic Acid Quantification, International Journal of Molecular Sciences 24(23) (2023) 16937. https://doi.org/10.3390/ijms242316937 DOI: https://doi.org/10.3390/ijms242316937
[47] P. T. Pınar, Hemn A. H. Barzani, H. S. Ali, Yavuz Yardım, Quantification of ferulic acid using square-wave voltammetric method at an unmodified boron-doped diamond electrode, Chemical Monthly 154 (2023) 1225-1233. https://doi.org/10.1007/s00706-023-03126-8 DOI: https://doi.org/10.1007/s00706-023-03126-8
[48] L. Luo, X. Wang, Q. Li, Y. Ding, J. Jia, D. Deng, Voltammetric Determination of Ferulic Acid by Didodecyldimethyl-ammonium Bromide/Nafion Composite Film-modified Carbon Paste Electrode, Analytical Science 26 (2010) 907-911. https://doi.org/10.2116/analsci.26.907 DOI: https://doi.org/10.2116/analsci.26.907
[49] G. Li, S. Liu, Y. Liu, X. Pang, M. Li, Y. Gong, Y. Wu, X. Guo, Au-doped nanostructured TiO2/C material derived from MIL-125 as a highly sensitive electrochemical sensor for ferulic acid, Journal of Coordination Chemistry 76 (2023) 1007-1019. https://doi.org/10.1080/00958972.2023.2221375 DOI: https://doi.org/10.1080/00958972.2023.2221375
Downloads
Published
Issue
Section
License
Copyright (c) 2025 Jamballi G. Manjunatha, Karnayana. P. Moulya
This work is licensed under a Creative Commons Attribution 4.0 International License.
How to Cite
Funding data
-
Department of Electronics Information Technology Biotechnology and Science and Technology
Grant numbers VGST/K-FIST L2/2022-23/GRD-1020
