Enhanced voltammetric detection of paracetamol by using carbon nanotube modified electrode as an electrochemical sensor

  • Madikeri M. Charithra Department of Chemistry, FMKMC College, Madikeri, Mangalore University Constituent College, Karnataka
  • Jamballi G. Manjunatha Department of Chemistry, FMKMC College, Madikeri, Mangalore University Constituent College, Karnataka
Keywords: Voltammetric studies, Electropolymerization, Methyl orange, Paracetamol, Detection limit

Abstract

New aspects associated with electro-catalytic activity of poly(methyl orange) modified carbon nanotube paste electrode (PMMCNTPE) towards the detection of paracetamol (PC) which is typically used worldwide as a pain reliever, were explored through implementation of cyclic voltammetry (CV) and differential pulse voltammetry (DPV) techniques. Bare carbon nanotube paste electrode (BCNTPE) was modified by methyl orange using the electro­polymerizing method. The effect of pH and influence of potential scan rate were resolved by means of CV technique. It was found that under optimized experimental conditions, PMMCNTPE imparts the analytical curve for PC in the concentration range of 2.0×10-6 – 5.0×10-5 M with detection limit of 3.8×10-8 M and limit of quantification of 1.2×10-8 M. The proposed sensor exhibited acceptable reproducibility, admirable stability, and adequate repeatability. The interference study of PC with dopamine (DA) and folic acid (FA) showed good selectivity of the designed sensor. The feasibility of the constructed electrochemical sensor to detect PC was successfully tested in some pharmaceutical formulations.

Downloads

Download data is not yet available.

References

F. R. Lichtenberg, International Journal of Health Care Finance and Economics 5 (2005) 47-73.

A. K. Wagner, J. D. Quick, D. Ross-Degnan, BMC Health Services Research 14 (2014) 1-6.

M. A. Mallah, S. H. Sherazi, M. I. Bhanger, S. A. Mahesar, M. A. Bajeer, Spectrochimica Acta Part A 141 (2015) 64-70.

H. Beitollahi, F. Garkani-Nejad, S. Tajik, M. R. Ganjali, Iranian Journal of Pharmaceutical Research 18 (2019) 80-90.

R. N. Goyal, V. K. Gupta, M. Oyama, N. Bachheti, Electrochemistry Communications 7 (2005) 803-807.

T. Skeika, M. Ferreira de Faria, N. Nagata, C. A. Pessoa, Journal of the Brazilian Chemical Society 19 (2008) 762-768.

S.J. Richard Prabakar, S.S. Narayanan, Talanta 72 (2007) 1818-1827.

A. U. Alam, Y. Qin, M. M. R. Howlader, N.-X. Hu, M. J. Deen, Sensors and Actuators B 254 (2018) 896–909.

S. F. Mbokou, M. Pontié, B. Razafimandimby, J. Bouchara, E. Njanja, I. Tonle Kenfack, Analytical and Bioanalytical Chemistry 408 (2016) 5895-5903

R. T. Kachoosangi, G. G. Wildgoose, R. G. Compton, Analytica Chimica Acta 618 (2008) 54–60.

A. M. Larson, J. Polson, R. J. Fontana, T. J. Davern, E. Lalani, L. S. Hynan, J. S. Reisch, F. V. Schiødt, G. Ostapowicz, A. O. Shakil, W. M. Lee, Hepatology 42 (2005) 1364–1372.

M. Mazer, J. Perrone, Journal of Medical Toxicology 4 (2008) 2-6.

N. T. Anh Thu, H. V. Duc, N. H. Phong, N. D. Cuong , N. T Vuong Hoan , D. Q. Khieu, Journal of Nanomaterials (2018) 1-15.

B. D Blair, J. P. Crago, C. J. Hedman, R. D. Klaper, Chemosphere 93 (2013) 2116–2123.

M. E. Bosch, A. J. Sánchez, F. S. Rojas, C. B. Ojeda, Journal of Pharmaceutical and Biomedical Analysis 42 (2006) 291–321.

M. K. Srivastava, S. Ahmad, D. Singh, I. C. Shukla, Analyst 110 (1985) 735–737.

K. G. Kumar, R. Letha, Journal of Pharmaceutical and Biomedical Analysis 15 (1997) 1725–1728.

G. Burgot, F. Auffret, J.-L. Burgot, Analytica Chimica Acta 343 (1997) 125–128.

W. Lohmann, U. Karst, Analytical and Bioanalytical Chemistry 386 (2006) 1701-1708.

H.-G. Lou, H. Yuan, Z.-R. Ruan, B. Jiang, Journal of Chromatography B 878 (2010) 682-688.

I. Baranowska, B. Kowalski, Water, Air and Soil Pollution 211 (2010) 417-425.

G. M. Hadad, S. Emara, W. M. Mahmoud, Talanta 79 (2009) 1360-1367.

M. G. Gioia, P. Andreatta, S. Boschetti, R. Gatti, Journal of Pharmaceutical and Biomedical Analysis 48 (2008) 331-339.

S. Zhao, W. Bai, H. Yuan, D. Xiao, Analytica Chimica Acta 559 (2006) 195-199.

W. Ruengsitagoon, S. Liawruangrath, A. Townshend, Talanta 69 (2006) 976-983.

Y.Z. Fang, D.J. Long, J.N. Ye, Analytica Chimica Acta 342 (1997) 13-21.

Sirajuddin, A. R. Khaskheli, A. Shah, M. I. Bhanger, A. Niaz, S. Mahesar, Spectrochimica Acta Part A: Molecular and Bimolecular Spectroscopy 68 (2007) 747-751.

N. Al-Zoubi, J. E. Koundourellis, S. Malamataris, Journal of Pharmaceutical and Biomedical Analysis 29 (2002) 459-467.

D. Šatinský, I. Neto, P. Solich, H. Sklenárová, M. Conceição, B. S. M. Montenegro, A. N. Araújo, Journal of Separation Science 27 (2004) 529-536.

M. Shalash, A. Salhin, B. Saad, I. A. Rahman, Journal of Liquid Chromatography and Related Technologies 36 (2013) 155-166.

M. S. M. Quintino, K. Araki, H. E. Toma, L. Angnes, Electroanalysis 14 (2002) 1629-1634.

H. Beitollahi, F. G. Nejad, Electroanalysis 28 (2016) 2237-2244.

H. Beitollahi, J. B. Raoof, H. Karimi-Maleh, R. Hosseinzadeh, Journal of Solid State Electrochemistry 16 (2012) 1701-1707.

H. Beitollahi, K. Movlaee, M. R. Ganjali, P. Norouzi, Journal of Electroanalytical Chemistry 799 (2017) 576- 582.

H. Beitollahi, S. Nekooei, M. Torkzadeh-Mahani, Talanta 188 (2018) 701-707.

V. K. Gupta, T. A. Saleh, Environmental Science and Pollution Research 20 (2013) 2828-2843.

K. Giribabu, Y. Haldorai, M. Rethinasabapathy, S.-C. Jang, R. Suresh, W.-S. Cho, Y.-K. Han, C. Roh, Y.-S. Huh, V. Narayanan, Current Applied Physics 17 (2017) 1114-1119.

C. Raril, J. G Manjunatha, Biomedical Journal of Science and Technical Research 9 (2018) 7149-7154.

M. Baccarin, F. A. Santos, F. C. Vicentini, V. Zucolotto, B. C. Janegitz, O. Fatibello-Filho, Journal of Electroanalytical Chemistry 799 (2017) 436-443.

N. Karikalan, R. Karthik, S.-M. Chen, M. Velmurugan, C. Karuppiah, Journal of Colloids and Interface Science 483 (2016) 109-117.

T. T. Minh, N. H. Phong, H. V. Duc, D. Q. Khieu, Journal of Materials Science 53 (2018) 2453-2471.

A. Wong, A. M. Santos, O. Fatibello-Filho, Diamonds and Related Materials 85 (2018) 68-73.

M. M. Charithra, J. G. Manjunatha, Materials Science for Energy Technologies 2 (2019) 365-371.

M.-P.N. Bui, C. A. Li, K. N. Han, X.-H. Pham, G.H. Seong, Sensors and Actuators B 174 (2012) 318-324.

S. Ashok Kumar, C. Tang, S. Chen, Talanta 76 (2008) 997-1005.

M. Li, L. Jing, Electrochimica Acta 52 (2007) 3250-3257.

S. Mehretie, S. Admassie, T. Hunde, M. Tessema, T. Solomon, Talanta 85 (2011) 1376-1382.

R. C. Saini, L. Gebresilassie, T. Hunde, M. Tirfu, R. Pal, International Journal of Chemistry and Pharmaceutial Sciences 4 (2016) 122-129.

B. C. Lourenção, R. A. Medeiros, R. C. Rocha-Filho, L. H. Mazo, O. Fatibello-Filho, Talanta 78 (2009) 748-752.

S. Machado, G. N. Calaça, J. P. da Silva, M. P. de Araujo, R. T. Boeré, C. A. Pessôa, K. Wohnrath, Journal of Electrochemical Society 164 (2017) B314-B320.

K. Asadpour-Zeynali, R. Amini, Electroanalysis 29 (2017) 635-642.

J. G. Manjunatha, Sensing and Bio-Sensing Research 16 (2017) 79-84.

Published
08-12-2019
Section
Electrochemical Science