ADMET & DMPK (ISSN 1848-7718) is an international, peer reviewed open-access Journal aiming for rapid dissemination of original research articles, review papers and comments in the broad areas of absorption, distribution, metabolism, excretion, toxicology and pharmacokinetics of drugs. The emphasis is on rapid publishing of articles of high scientific quality to make them freely available to researchers worldwide.



Editor-in-chief: Kin Tam


Associate Editors:

  • Godefridus J. Peters - Oncology
  • Yin Tian - Neuroscience
  • Klara Valko - Analytical Science and Drug Discovery
  • Naveed Shaik - Modelling and Simulation
  • Kiyohiko Sugano - Biopharmaceutics & Drug Delivery


Editorial Board

Imprint information

ISSN 1848-7718


Abstracting and indexing: WoS Emerging Source Citation Index (ESCI), SCOPUS, International Pharmaceutical Abstracts, Google scholar, DOAJ, CrossRef, ROAD, Chemical abstracts





7th IAPC Meeting

Ritsumeikan University, Japan, August 28-30, 2018






: Special issue: Physiologically based pharmacokinetic (PBPK) modeling and simulation in drug discovery and development

Guest editors: Abdul Naveed Shaik and Ansar Ali Khan  
Posted: 1970-01-01 More...

: Special issue: Applications of biophysical techniques in drug discovery and development

Guest editor: Tatjana Verbić  
Posted: 1970-01-01 More...
More Announcements...

Vol 6, No 2 (2018)

Chromatographic techniques to support ADMET&DMPK in early drug discovery
Guest editor: Klara Livia Valko

Table of Contents


Chromatographic technique to support ADMET&DMPK in early drug discovery PDF
Klara Livia Valko 71-73


The role and impact of high throughput biomimetic measurements in drug discovery PDF
Shenaz Bunally, Robert J Young 74-84
Leveraging chromatography based physicochemical properties for efficient drug design PDF
Gilles H. Goetz, Marina Shalaeva 85-104
Cocrystal solubility-pH and drug solubilization capacity of sodium dodecyl sulfate – mass action model for data analysis and simulation to improve design of experiments PDF
Alex Avdeef 105-139

Original Scientific Articles

Estimation of skin permeation by liquid chromatography PDF
Sara Soriano-Meseguer, Elisabet Fuguet, Adriana Port, Martí Rosés 140-152
Lipophilicity determination of acidic compounds: MEEKC as a reliable high-throughput methodology PDF
Xavier Subirats, Lidia Redón, Martí Rosés 153-161
Application of biomimetic HPLC to estimate lipophilicity, protein and phospholipid binding of potential peptide therapeutics PDF
Klara Livia Valko, Gabriela Ivanova-Berndt, Paul Beswick, Mark Kindey, Dorothy Ko 162-175
In vitro biomimetic HPLC and in vivo characterisation of GM6, an endogenous regulator peptide drug candidate for amyotrophic lateral sclerosis PDF
Klara Livia Valko, Mark Kindy, James Evans, Dorothy Ko 176-189
Peptide retention time prediction for immobilized artificial membrane phosphatidylcholine stationary phase: method development and preliminary observations PDF
Daniel Gussakovsky, Haley Neustaeter, Victor Spicer, Oleg Krokhine 190-199

ISSN 1848-7718