Solubility special issue

• Can small drugs predict the intrinsic aqueous solubility of ‘beyond Rule of 5’ big drugs?

  Alex Avdeef, Manfred Kansy

  Published 25-04-2020;

  DOI: https://doi.org/10.5599/admet.794

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• Mechanistic modeling of gastrointestinal motility with integrated dissolution for simulating drug absorption

  Kevin Charles Johnson

  Published 09-06-2020;

  DOI: https://doi.org/10.5599/admet.829

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• Three machine learning models for the 2019 Solubility Challenge

  John Mitchell

  Published 15-06-2020;

  DOI: https://doi.org/10.5599/admet.835

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• GAFF/IPolQ-Mod+LJ-Fit: Optimized force field parameters for solvation free energy predictions

  Andreas Mecklenfeld, Gabriele Raabe

  Published 28-06-2020;

  DOI: https://doi.org/10.5599/admet.837

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• Solubility and ADMET profiles of short oligomers of lactic acid

  Daniela Dascălu, Diana Larisa Roman, Madalina Filip, Alecu Aurel Ciorsac, Vasile Ostafe, Adriana Isvoran

  Published 28-06-2020;

  DOI: https://doi.org/10.5599/admet.843

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• Solubility of proteins

  Mauno Vihinen

  Published 28-06-2020;

  DOI: https://doi.org/10.5599/admet.831

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• In vitro release studies of furosemide reference tablets: influence of agitation rate, USP apparatus and dissolution media

  Raúl Medina-López, Sergio Guillén-Moedano, Marcela Hurtado

  Published 29-06-2020;

  DOI: https://doi.org/10.5599/admet.801

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• Supercritical fluid technology for solubilization of poorly water soluble drugs via micro- and naonosized particle generation

  Shashi Kiran Misra, Kamla Pathak

  Published 29-06-2020;

  DOI: https://doi.org/10.5599/admet.811

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• Electrospun nanofibers: A nanotechnological approach for drug delivery and dissolution optimization in poorly water-soluble drugs

  Luis Castillo-Henríquez, Rolando Vargas-Zúñiga, Jorge Pacheco-Molina, Jose Vega-Baudrit

  Published 05-07-2020;

  DOI: https://doi.org/10.5599/admet.844

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• Solubility prediction in the bRo5 chemical space: where are we right now?

  Giuseppe Ermondi, Vasanthanathan Poongavanam, Maura Vallaro, Jan Kihlberg, Giulia Caron

  Published 08-07-2020;

  DOI: https://doi.org/10.5599/admet.834

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  • Supplementary data

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• Image-based dissolution analysis for tracking the surface stability of amorphous powders

  Jernej Štukelj, Mikael Agopov, Jouko Yliruusi, Clare J. Strachan, Sami Svanbäck

  Published 13-07-2020;

  DOI: https://doi.org/10.5599/admet.839

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• Dissolution of an ensemble of differently shaped poly-dispersed drug particles undergoing solubility reduction: mathematical modelling

  Michela Abrami, Lucia Grassi, Rosario Di Vittorio, Dritan Hasa, Beatrice Perissutti, Dario Voinovich, Gabriele Grassi, Italo Colombo, Mario Grassi

  Published 14-07-2020;

  DOI: https://doi.org/10.5599/admet.841

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• The effect of drug ionization on lipid-based formulations for the oral delivery of anti-psychotics

  Tahlia R Meola, Kara Paxton, Paul Joyce, Hayley B Schultz, Clive A Prestidge

  Published 17-07-2020;

  DOI: https://doi.org/10.5599/admet.830

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• ADME Prediction with KNIME: In silico aqueous solubility models based on supervised recursive machine learning approaches

  Gabriela Falcón-Cano, Christophe Molina, Miguel Angel Cabrera-Pérez

  Published 08-08-2020;

  DOI: https://doi.org/10.5599/admet.852

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  • Supplementary data

  

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