A novel electrochemical sensor for differential pulse voltammetric determination of droxidopa

Original scientific paper

Authors

  • Shatha Abd Aljabbar Ismael Department of Biology, College of Education for Pure Science, University of Kerbala, Iraq https://orcid.org/0009-0006-5932-6162
  • Mohanad Kadhem Alshujery Ministry of Education, General Directorate of Education, Al-Karkh the Second, Iraq https://orcid.org/0000-0003-1935-4784
  • Hasan Ali Alsailawi Department of Basic Sciences, College of Dentistry, University of Kerbala, 56001, Karbala, Iraq https://orcid.org/0009-0008-9431-3994
  • Mustafa Mudhafar Centre for Research on Environment and Renewable Energy, University of Kerbala, Iraq and Department of Therapeutic Nutrition Technologies, Al Taff University College, Kerbala, Iraq https://orcid.org/0000-0002-3785-7396
  • Hussein Ali Al-Bahrani College of Nursing, University of Al-Ameed, Iraq and Department of Chemistry, College of Education for Pure Science, University of Kerbala, Iraq https://orcid.org/0000-0002-9637-3359

DOI:

https://doi.org/10.5599/jese.3627

Keywords:

Neurotransmitters, Parkinson's disease, synthetic amino acid, modified electrode

Abstract

This study prepares a voltammetric sensor for determining droxidopa (DXP). A carbon paste electrode (CPE) modified with ZnO-CuO nanoplates (ZC/CPE) was used to create the voltammetric sensor. DXP was determined using the ZC/CPE sensor and differential pulse voltammetry. ZC/CPE's anodic current response showed a linear correlation with the DXP concentration between 0.1 and 300.0 μM under ideal experimental conditions, indicating a sensitivity of 0.181 μA μM-1. The ZC/CPE sensor's limit of detection for measuring DXP was 0.06 μM. The technique was used to measure DXP in human urine and water samples. 

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References

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Published

19-10-2026

Issue

Vol. 16 No. SI (2026)

Section

Electroanalytical chemistry

License

Copyright (c) 2026 Shatha Abd Aljabbar Ismael, Mohanad Kadhem Alshujery, Hasan Ali Alsailawi, Mustafa Mudhafar, Hussein Ali Al-Bahrani

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

A novel electrochemical sensor for differential pulse voltammetric determination of droxidopa: Original scientific paper. (2026). Journal of Electrochemical Science and Engineering, 16(SI), Article 3627. https://doi.org/10.5599/jese.3627

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