Block relevance (BR) analysis and polarity descriptors in property-based drug design

Giuseppe Ermondi; Giulia Caron

doi:10.5599/admet.532

Block relevance (BR) analysis and polarity descriptors in property-based drug design

Authors

Giuseppe Ermondi University of Torino (I)
Giulia Caron University of Torino (I)

DOI:

https://doi.org/10.5599/admet.532

Keywords:

ADME, hydrogen bonding, IAM, QSPR, PLS, PSA, VIP

Abstract

Block Relevance (BR) analysis is a tool to interpret QSPR/PLS models which can provide the information content of any physicochemical determinant used in property-based drug discovery; its application for the characterization of experimental polarity descriptors is discussed.

Downloads

Download data is not yet available.

Downloads

Published

22-09-2018

Issue

Vol. 6 No. 3 (2018)

Section

Reviews

How to Cite

Block relevance (BR) analysis and polarity descriptors in property-based drug design. (2018). ADMET and DMPK, 6(3), 215-224. https://doi.org/10.5599/admet.532