NiMoO4 nanosheets modified carbon paste electrode for simultaneous determination of epinine and dobutamine

Original scientific paper

Authors

  • Falah H. Abdullah Department of Forensic Sciences, College of Health and Medical Technology, National University of Science and Technology, Dhi Qar, Iraq https://orcid.org/0009-0009-2701-2275
  • Ibrahim Ayad Jihad Department of Chemistry and Biochemistry, Al-Zahraa College of Medicine, University of Basrah, Iraq https://orcid.org/0009-0008-7245-0437
  • Talib Saddam Mohsin Department of Anesthesia Techniques, Kut University College, Wasit, Iraq https://orcid.org/0009-0003-1131-5630
  • Mustafa Mudhafar Faculty of Medical Applied Sciences, University of Kerbala, Karbala, Iraq and Al-Taff University College, Kerbala, Iraq https://orcid.org/0000-0002-3785-7396
  • Raed Muslim Muhibes Department of Biochemistry, College of Medicine Misan University, Iraq https://orcid.org/0000-0002-4835-0873

DOI:

https://doi.org/10.5599/jese.2718

Keywords:

Electrochemical sensor, deoxyepinephrine, catecholamine, cardiovascular disease, dobutamine

Abstract

In this work, a carbon paste electrode was modified with ionic liquids and NiMoO4 nanosheets (NMs/IL/CPE) for voltammetric epinine detection. The NMs/IL/CPE showed good electro­catalytic activity for epinine oxidation compared to unmodified CPE. The limit of detection is 0.05 μM, and under ideal circumstances, the oxidation peak currents of epinine show a linear relationship with epinine concentration from 0.1 to 300.0 μM. Additionally, when dobutamine was present, the NMs/IL/CPE showed good activity toward epinine determi­na­tion. Its appropriateness for the simultaneous detection of these two medicines using dif­ferential pulse voltammetry is shown by the separation of the oxidation peak potentials of 200 mV. Lastly, epinine and dobutamine analysis in real specimens confirmed the proposed sensor's applicability with outstanding findings (recovery 96.0 to 103.5 %, and relative standard deviation <3.6 %).

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Published

01-05-2025

Issue

Vol. 15 No. 4 (2025)

Section

Electroanalytical chemistry

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Copyright (c) 2025 Falah H. Abdullah, Ibrahim Ayad Jihad, Talib Saddam Mohsin, Mustafa Mudhafar, Raed Muslim Muhibes

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This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

NiMoO4 nanosheets modified carbon paste electrode for simultaneous determination of epinine and dobutamine: Original scientific paper. (2025). Journal of Electrochemical Science and Engineering, 15(4), 2718. https://doi.org/10.5599/jese.2718