Determination of nevirapine in the presence of cucurbit(7)uril with a gold electrode

Authors

  • Ana E. Esteva Departamento de Química Analítica, Facultad de Química, Universidad de La Habana, La Habana 10400
  • Elías Blanco Departamento de Química Analítica y Análisis Instrumental, Facultad de Ciencias, Universidad Autónoma de Madrid, Cantoblanco 28049, Madrid
  • Juan J. Piña Departamento de Química Analítica, Facultad de Química, Universidad de La Habana, La Habana 10400
  • Abel I. Balbin Departamento de Química Analítica, Facultad de Química, Universidad de La Habana, La Habana 10400
  • Carmen Quintana Departamento de Química Analítica y Análisis Instrumental, Facultad de Ciencias, Universidad Autónoma de Madrid, Cantoblanco 28049, Madrid
  • Pedro Hernández Departamento de Química Analítica y Análisis Instrumental, Facultad de Ciencias, Universidad Autónoma de Madrid, Cantoblanco 28049, Madrid

DOI:

https://doi.org/10.5599/jese.2014.0043

Abstract

The electrochemical oxidation of nevirapine, an anti-HIV drug, at a gold electrode was studied by voltammetric techniques. Nevirapine showed a signal that interfered with a working electrode wave. This interference was solved by the use of cucurbit(7)uril allowing nevirapine to be determined in tablets (80.4 % recovery, presence of stavudine and lamivudine) and urine (98.4 %).

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Published

25-01-2014

Issue

Vol. 4 No. 1 (2014)

Section

Electrochemical Engineering

How to Cite

Determination of nevirapine in the presence of cucurbit(7)uril with a gold electrode. (2014). Journal of Electrochemical Science and Engineering, 4(1), 37-44. https://doi.org/10.5599/jese.2014.0043