Block relevance (BR) analysis and polarity descriptors in property-based drug design

  • Giuseppe Ermondi University of Torino (I)
  • Giulia Caron University of Torino (I)
Keywords: ADME, hydrogen bonding, IAM, QSPR, PLS, PSA, VIP

Abstract

Block Relevance (BR) analysis is a tool to interpret QSPR/PLS models which can provide the information content of any physicochemical determinant used in property-based drug discovery; its application for the characterization of experimental polarity descriptors is discussed.

Downloads

Download data is not yet available.
Published
22-09-2018
Section
Reviews