A newly designed nano metal-organic framework of yttrium-benzenetricarboxylic acid: synthesis, characterization, antimicrobial and electrochemical properties
Original scientific paper
DOI:
https://doi.org/10.5599/jese.3320Keywords:
Doxorubicin drug, Graphite screen printed electrode, chemical modification, functional porous materials, antibacterial tests, biological real samplesAbstract
In this work, a metal-organic framework based on yttrium and benzene tricarboxylic acid
(Y-BTC-MOF) was synthesized via solvothermal synthesis. Y-BTC-MOF was characterized using energy-dispersive X-ray spectroscopy, field emission scanning electron microscopy, X-ray diffraction pattern, Fourier transform infrared spectroscopy, transmission electron microscopy and an elemental mapping image. Also, Y-BTC-MOF was applied for the modification of a screen printed electrode. The modified electrode was used for voltammetric determination of doxorubicin in the calibration range of 0.002 to 110.0 µM.
Downloads
References
[1] C. Calderón-Figueroa, A. Castillo-Delgado, L. Rodriguez-Osiac, E. A. Castellón, K. Puschel, Ó. Arteaga, A. Fuentes-García, Institutional practices for cancer: Comparison of social and health care along disease trajectory in five countries with high survival rates, Journal of Cancer Policy 21 (2026) 100733. https://doi.org/10.1016/j.jcpo.2026.100733 DOI: https://doi.org/10.1016/j.jcpo.2026.100733
[2] D. G. Passey, R. Healy, J. Qualls, A. Halwani, B. C. Sauer, Pharmacist-led collaborative medication management programs for oral antineoplastic therapies: A systematic literature review, Journal of the American Pharmacists Association 61 (2021) e7-e18. https://doi.org/10.1016/j.japh.2020.12.005 DOI: https://doi.org/10.1016/j.japh.2020.12.005
[3] K. A. Madurani, Y. Triana, A. Wafi, S. R. Sari, S. N. Jenie, N. N. Zain, P. Tiadeka, Graphene innovations: transforming drug detection technologies for clinical and environmental applications, Microchemical Journal 17 (2026) 117743. https://doi.org/10.1016/j.microc.2026.117743 DOI: https://doi.org/10.1016/j.microc.2026.117743
[4] M. Qiu, Z. Wang, Y. Teng, M. Li, F. Wu, Y. Tian, Targeting lncRNA-Mediated Networks to Overcome Doxorubicin Resistance in Cancer, Critical Reviews in Oncology/Hematology 13 (2026) 105214. https://doi.org/10.1016/j.critrevonc.2026.105214 DOI: https://doi.org/10.1016/j.critrevonc.2026.105214
[5] L. Wang, S. Gu, F. Yan, C. Shen, Rapid determination of liposomal encapsulation efficiency of doxorubicin using an integrated separation-enrichment-sensing electrochemical platform based on bipolar vertically-ordered mesoporous silica nanochannel arrays, Microchemical Journal 19 (2025) 116658. https://doi.org/10.1016/j.microc.2025.116658 DOI: https://doi.org/10.1016/j.microc.2025.116658
[6] N. Erk, G. Kurtay, W. Bouali, A. A. Genç, Molecular binding and electrochemical detection synergy: A study on doxorubicin using nanodiamond-glassy carbon electrodes, Microchemical Journal 210 (2025) 112907. https://doi.org/10.1016/j.microc.2025.112907 DOI: https://doi.org/10.1016/j.microc.2025.112907
[7] Z. Wang, H. Wang, M. Cao, Y. Liu, Preparation of electrochemical sensor for detection of cancer medicine doxorubicin based on multi-walled carbon nanotube composites modified electrode, Alexandria Engineering Journal 93 (2024) 51-58. https://doi.org/10.1016/j.aej.2024.02.067 DOI: https://doi.org/10.1016/j.aej.2024.02.067
[8] E. Lulek, J. Soleymani, M. Molaparast, Y. N. Ertas, Electrochemical sensing of doxorubicin hydrochloride under sodium alginate antifouling conditions using silver nanoparticles modified glassy carbon electrodes, Talanta 265 (2023) 124846. https://doi.org/10.1016/j.talanta.2023.124846 DOI: https://doi.org/10.1016/j.talanta.2023.124846
[9] N. A. Salman, I. A. Jassem, I. N. Taeb, A simple UiO-66-NH2@ MWCNTs based electrochemical sensor for the sensitive detection of metronidazole, ADMET & DMPK 14 (2026) 2940. https://doi.org/10.5599/admet.2940 DOI: https://doi.org/10.5599/admet.2940
[10] S. Deepa, B. K. Swamy, K. V. Pai, A surfactant SDS modified carbon paste electrode as an enhanced and effective electrochemical sensor for the determination of doxorubicin and dacarbazine its applications: A voltammetric study, Journal of Electroanalytical Chemistry 879 (2020) 114748. https://doi.org/10.1016/j.jelechem.2020.114748 DOI: https://doi.org/10.1016/j.jelechem.2020.114748
[11] A. Obaid Imarah, N. Hasan, M. G. Alabbasi, ZnO-modified carbon paste electrode for electrochemical sensing of dopamine in the presence of tyrosine, ADMET & DMPK 13 (2025) 3010. https://doi.org/10.5599/admet.3010 DOI: https://doi.org/10.5599/admet.3010
[12] A. A. Bhoite, N. L. Tarwal, Metal-organic frameworks (MOFs) and their composites as electrode materials for supercapacitor applications, Sustainable Materials and Technologies 11 (2026) e01956. https://doi.org/10.1016/j.susmat.2026.e01956 DOI: https://doi.org/10.1016/j.susmat.2026.e01956
[13] J. Wang, M. Xu, X. Liang, Y. Zhang, D. Yang, L. Pan, W. Fang, C. Zhu, F. Wang, Development of a novel 2D Ni-MOF derived NiO@ C nanosheet arrays modified Ti/TiO2NTs/PbO2 electrode for efficient electrochemical degradation of salicylic acid wastewater, Separation and Purification Technology 263 (2021) 118368. https://doi.org/10.1016/j.seppur.2021.118368 DOI: https://doi.org/10.1016/j.seppur.2021.118368
[14] F. Khazaal, Q. M. Salih, R. Radi Karabat, R. Muslim Muhibes Electrochemical determination of calcium folinate in the presence of methotrexate and 5-fluorouracil using UiO-66/CdS composite modified screen-printed carbon electrode, ADMET & DMPK 13 (2025) 2897. https://doi.org/10.5599/admet.2897 DOI: https://doi.org/10.5599/admet.2897
[15] M. A. Azzam, A. Ahmad, A. A. Labib, W.A. Mohamed, A. K. El-Sawaf, H. T. Handal, Advanced Screen-Printed Electrodes: Shaping the Future of Electrochemical Wastewater Analysis: A Review, Electrochimica Acta 561 (2026) 148646. https://doi.org/10.1016/j.electacta.2026.148646 DOI: https://doi.org/10.1016/j.electacta.2026.148646
[16] S. Hong, S. Oh, E. Kim, E. Park, H. C. Chun, I. T. Kim, Y. R. Kim, Fabrication of screen-printed electrodes with long-term stability for voltammetric and potentiometric applications, Sensors and Actuators Reports 8 (2024) 100234. https://doi.org/10.1016/j.snr.2024.100234 DOI: https://doi.org/10.1016/j.snr.2024.100234
[17] P. Kelíšková, O. Matvieiev, L. Janíková, R. Šelešovská, Recent advances in the use of screen-printed electrodes in drug analysis: A review, Current Opinion in Electrochemistry 42 (2023) 101408. https://doi.org/10.1016/j.coelec.2023.101408 DOI: https://doi.org/10.1016/j.coelec.2023.101408
[18] M. Sher, A. Faheem, W. Asghar, S. Cinti, Nano-engineered screen-printed electrodes: A dynamic tool for detection of viruses, TrAC Trends in Analytical Chemistry 143 (2021) 116374. https://doi.org/10.1016/j.trac.2021.116374 DOI: https://doi.org/10.1016/j.trac.2021.116374
[19] L. M. Chen, J. Liu, J. C. Chen, S. Shi, C. P. Tan, K. C. Zheng, L. N. Ji, Experimental and theoretical studies on the DNA-binding and spectral properties of water-soluble complex [Ru (MeIm)4 (dpq)]2+, Journal of Molecular Structure 881 (2008) 156-166. https://doi.org/10.1016/j.molstruc.2007.09.010 DOI: https://doi.org/10.1016/j.molstruc.2007.09.010
[20] E. Sadeghi, N. S. Peighambardoust, S. Chamani, U. Aydemir, Designing in situ grown ternary oxide/2D Ni-BDC MOF nanocomposites on nickel foam as efficient electrocatalysts for electrochemical water splitting, ACS Materials Au 3 (2022) 143-163. https://doi.org/10.1021/acsmaterialsau.2c00073 DOI: https://doi.org/10.1021/acsmaterialsau.2c00073
[21] R. Srinivasan, R. Yogamalar, A. Chandra Bose, Synthesis and structural studies on nanocrystalline yttrium oxide, Advanced Science Letters 2 (2009) 65-69. https://doi.org/10.1166/asl.2009.001 DOI: https://doi.org/10.1166/asl.2009.001
[22] F. L. Presti, A. Borzì, A. L. Pellegrino, P. Rossi, P. Paoli, G. Malandrino, Morphology controlled synthesis of yttrium metal–organic frameworks with a tritopic ligand, Results in Chemistry 4 (2022) 100640. https://doi.org/10.1016/j.rechem.2022.100640 DOI: https://doi.org/10.1016/j.rechem.2022.100640
[23] S. M. Tala-Tapeh, N. Mahmoodi, A. Vaziri, Synthesis of bis-chalcones based on 5, 5΄-methylenebis (2-hydroxybenzaldehyde) and screening their antibacterial activity, Journal of Applied Chemistry 9 (2015) 53-58. https://Chemistry.journals.semnan.ac.ir
[24] A. K. Chatterjee, R. Chakraborty, T. Basu, Mechanism of antibacterial activity of copper nanoparticles, Nanotechnology 25 (2014) 135101. https://doi.org/10.1088/0957-4484/25/13/135101 DOI: https://doi.org/10.1088/0957-4484/25/13/135101
Downloads
Published
Issue
Section
License
Copyright (c) 2026 Sarah M. Mohsen, Zeina Haider Abbas, Saja Haider Fadhil, Noor Kareem Aead

This work is licensed under a Creative Commons Attribution 4.0 International License.


