Vol. 6 No. 2 (2018) | ADMET and DMPK

Vol. 6 No. 2 (2018)

Chromatographic techniques to support ADMET&DMPK in early drug discovery
Guest editor: Klara Livia Valko

Published: 16-06-2018

Editorial

Chromatographic technique to support ADMET&DMPK in early drug discovery

Klara Livia Valko

ADMET and DMPK, Vol. 6 No. 2 (2018), 71-73

Published 16-06-2018;

DOI: https://doi.org/10.5599/admet.559
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Reviews

The role and impact of high throughput biomimetic measurements in drug discovery

Shenaz Bunally, Robert J Young

ADMET and DMPK, Vol. 6 No. 2 (2018), 74-84

Published 16-06-2018;

DOI: https://doi.org/10.5599/admet.530
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Leveraging chromatography based physicochemical properties for efficient drug design

Gilles H. Goetz, Marina Shalaeva

ADMET and DMPK, Vol. 6 No. 2 (2018), 85-104

Published 16-06-2018;

DOI: https://doi.org/10.5599/admet.529
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Cocrystal solubility-pH and drug solubilization capacity of sodium dodecyl sulfate – mass action model for data analysis and simulation to improve design of experiments

Alex Avdeef

ADMET and DMPK, Vol. 6 No. 2 (2018), 105-139

Published 16-06-2018;

DOI: https://doi.org/10.5599/admet.505
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Original Scientific Articles

Estimation of skin permeation by liquid chromatography

Sara Soriano-Meseguer, Elisabet Fuguet, Adriana Port, Martí Rosés

ADMET and DMPK, Vol. 6 No. 2 (2018), 140-152

Published 16-06-2018;

DOI: https://doi.org/10.5599/admet.512
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Lipophilicity determination of acidic compounds: MEEKC as a reliable high-throughput methodology

Xavier Subirats, Lidia Redón, Martí Rosés

ADMET and DMPK, Vol. 6 No. 2 (2018), 153-161

Published 16-06-2018;

DOI: https://doi.org/10.5599/admet.491
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Application of biomimetic HPLC to estimate lipophilicity, protein and phospholipid binding of potential peptide therapeutics

Klara Livia Valko, Gabriela Ivanova-Berndt, Paul Beswick, Mark Kindey, Dorothy Ko

ADMET and DMPK, Vol. 6 No. 2 (2018), 162-175

Published 16-06-2018;

DOI: https://doi.org/10.5599/admet.544
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In vitro biomimetic HPLC and in vivo characterisation of GM6, an endogenous regulator peptide drug candidate for amyotrophic lateral sclerosis

Klara Livia Valko, Mark Kindy, James Evans, Dorothy Ko

ADMET and DMPK, Vol. 6 No. 2 (2018), 176-189

Published 16-06-2018;

DOI: https://doi.org/10.5599/admet.547
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Peptide retention time prediction for immobilized artificial membrane phosphatidylcholine stationary phase: method development and preliminary observations

Daniel Gussakovsky, Haley Neustaeter, Victor Spicer, Oleg Krokhine

ADMET and DMPK, Vol. 6 No. 2 (2018), 190-199

Published 16-06-2018;

DOI: https://doi.org/10.5599/admet.520
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