An electrochemical sensing platform based on a modified carbon paste electrode with graphene/Co3O4 nanocomposite for sensitive propranolol determination
DOI:
https://doi.org/10.5599/admet.1705Keywords:
Carbon paste electrodes, graphene/Co3O4 nanocomposite, differential pulse voltammetry, propranolol
Abstract
A simple and sensitive method for the determination of propranolol using a modified carbon paste electrode with graphene/Co3O4 nanocomposite was presented. The electrochemical measurements of propranolol are studied using differential pulse voltammetry, cyclic voltammetry and chronoamperometry. The graphene/Co3O4 nanocomposite exhibits excellent catalytic activity towards the electrochemical oxidation of propranolol in phosphate buffer solution of pH 7.0. The graphene/Co3O4 nanocomposite facilitates the determination of propranolol in the concentration range 1.0–300.0 μM and a detection limit and sensitivity of 0.3 μM. and 0.1275 μA/μM were achieved.
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