Electroanalysis of tert-butylhydroquinone in food products using a paste electrode enlarged with single wall carbon nanotubes as catalyst

Original scientific paper


  • Niloofar Dehdashtian Department of Food Science and Technology, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran https://orcid.org/0009-0001-8920-4047
  • Seyed-Ahmad Shahidi Department of Food Science and Technology, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran https://orcid.org/0000-0001-5667-2875
  • Azade Ghorbani-HasanSaraei Department of Food Science and Technology, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran https://orcid.org/0000-0001-9756-5179
  • Shabnam Hosseini Department of Materials Science and Engineering, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran https://orcid.org/0000-0002-6683-7407
  • Mohammad Ahmadi Department of Food Hygiene, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran https://orcid.org/0000-0002-4909-4365




Food analysis, electroanalysis, modified electrode, carbon paste, voltammetry
Graphical Abstract


In this study, an electrochemical sensor was introduced as a simple and fast electro­analytical tool to monitor and sensing of tert-butylhydroquinone (TBHQ) in food products. The suggested electrochemical sensor is fabricated by modification of paste electrode (PE) by single wall carbon nanotubes (SWCNTs) as nanocatalyst. The oxidation current of TBHQ was improved by about 2.62 times and its oxidation potential was reduced by about 50 mV after using SWCNTs as conductive catalyst on a carbon paste matrix. The oxidation current of TBHQ showed a linear dynamic range of 0.05 to 390 µM in the sensing process using SWCNTs/PE as the electroanalytical sensor. On the other hand, SWCNTs/PE successfully monitored TBHQ with a detection limit of 10 nM at optimum conditions. The real sample analysis data clearly showed a recovery range of 97.2 to 104.3 %, which is very interesting for a new analytical tool in the food-sensing process.


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M. Ghalkhani, N. Zare, F. Karimi, C. Karaman, M. Alizadeh, Y. Vasseghian, Recent advances in Ponceau dyes monitoring as food colorant substances by electrochemical sensors and developed procedures for their removal from real samples, Food and Chemical Toxicology, (2022) 112830. https://doi.org/10.1016/j.fct.2022.112830

S. Cheraghi, F. Shalali, M.A. Taher, Kojic acid exploring as an essential food additive in real sample by a nanostructure sensor amplified with ionic liquid, Journal of Food Measurement and Characterization 17 (2023) 1728-1734. https://doi.org/10.1007/s11694-022-01738-y

J.A. Buledi, A.R. Solangi, A. Mallah, Z.-u.-H. Shah, S.T. Sherazi, M.R. Shah, A. Hyder, S. Ali, Electrochemical monitoring of isoproturon herbicide using NiO/V2O5/rGO/GCE, Journal of Food Measurement and Characterization 17 (2023) 1628-1639. https://doi.org/10.1007/s11694-022-01733-3

H. Karimi-Maleh, M. Ghalkhani, Z.S. Dehkordi, M. M. Tehran, J. Singh, Y. Wen, M. Baghayeri, J. Rouhi, L. Fu, S. Rajendran, MOF-enabled pesticides as developing approach for sustainable agriculture and reducing environmental hazards, Journal of Industrial and Engineering Chemistry 129 (2023) 105-123. https://doi.org/10.1016/j.jiec.2023.08.044

F. Khademi, S.N. Raeisi, M. Younesi, A. Motamedzadegan, K. Rabiei, M. Shojaei, H. Rokni, M. Falsafi, Effect of probiotic bacteria on physicochemical, microbiological, textural, sensory properties and fatty acid profile of sour cream, Food and Chemical Toxicology 166 (2022) 113244. https://doi.org/10.1016/j.fct.2022.113244

S.N. Raeisi, H.B. Ghoddusi, E.J. Boll, N. Farahmand, B. Stuer-Lauridsen, E. Johansen, J.P. Sutherland, L.I.I. Ouoba, Antimicrobial susceptibility of bifidobacteria from probiotic milk products and determination of the genetic basis of tetracycline resistance in Enterococcus species after in vitro conjugation with Bifidobacterium animalis subsp. lactis, Food Control 94 (2018) 205-211. https://doi.org/10.1016/j.foodcont.2018.07.016

F. Fazeli, S.M.S. Ardabili, Z. Piravivanak, M. Honarvar, N. Mooraki, Optimization of extraction conditions for polycyclic aromatic hydrocarbons determination in smoked rice using the high performance liquid chromatography-fluorescence detection, Journal of Food Measurement and Characterization 14 (2020) 1236-1248. https://doi.org/10.1007/s11694-020-00372-w

K.N. Waliszewski, V.T. Pardio, S.L. Ovando, A simple and rapid HPLC technique for vanillin determination in alcohol extract, Food Chemistry 101 (2007) 1059-1062. https://doi.org/10.1016/j.foodchem.2006.03.004

R. Rebane, I. Leito, S. Yurchenko, K. Herodes, A review of analytical techniques for determination of Sudan I–IV dyes in food matrixes, Journal of Chromatography A 1217 (2010) 2747-2757. https://doi.org/10.1016/j.chroma.2010.02.038

Q. Xiang, Y. Gao, Y. Xu, E. Wang, Capillary electrophoresis-amperometric determination of antioxidant propyl gallate and butylated hydroxyanisole in foods, Analytical Sciences 23 (2007) 713-717. https://doi.org/10.2116/analsci.23.713

N. Ermis, N. Zare, R. Darabi, M. Alizadeh, F. Karimi, J. Singh, S.-A. Shahidi, E.N. Dragoi, M.B. Camarada, M. Baghayeri, Recent advantage in electrochemical monitoring of gallic acid and kojic acid: a new perspective in food science, Journal of Food Measurement and Characterization 17 (2023) 3644-3653. https://doi.org/10.1007/s11694-023-01881-0

S.-A. Shahidi, Effect of solvent type on ultrasound-assisted extraction of antioxidant compounds from Ficaria kochii: Optimization by response surface methodology, Food and Chemical Toxicology 163 (2022) 112981. https://doi.org/10.1016/j.fct.2022.112981

S.M. Razi, A. Motamedzadegan, L. Matia-Merino, S.-A. Shahidi, A. Rashidinejad, The effect of pH and high-pressure processing (HPP) on the rheological properties of egg white albumin and basil seed gum mixtures, Food Hydrocolloids 94 (2019) 399-410. https://doi.org/10.1016/j.foodhyd.2019.03.029

M. Vardini, N. Abbasi, A. Kaviani, M. Ahmadi, E. Karimi, Graphite electrode potentiometric sensor modified by surface imprinted silica gel to measure valproic acid, Chemical Methodologies 6 (2022) 398-408. https://doi.org/10.22034/chemm.2022.328620.1437

S. Saghiri, M. Ebrahimi, M.R. Bozorgmehr, Electrochemical amplified sensor with MgO nanoparticle and ionic liquid: A powerful strategy for methyldopa analysis, Chemical Methodologies 5 (2021) 234-239. https://doi.org/10.22034/chemm.2021.128530

W.H. Danial, N.A. Norhisham, A.F. Ahmad Noorden, Z. Abdul Majid, K. Matsumura, A. Iqbal, A short review on electrochemical exfoliation of graphene and graphene quantum dots, Carbon Letters 31 (2021) 371-388. https://doi.org/10.1007/s42823-020-00212-3

Y.F. Mustafa, G. Chehardoli, S. Habibzadeh, Z. Arzehgar, Electrochemical detection of sulfite in food samples, Journal of Electrochemical Science and Engineering 12 (2022) 1061-1079. https://doi.org/10.5599/jese.1555

M. Akbari, M.S. Mohammadnia, M. Ghalkhani, M. Aghaei, E. Sohouli, M. Rahimi-Nasrabadi, M. Arbabi, H.R. Banafshe, A. Sobhani-Nasab, Development of an electrochemical fentanyl nanosensor based on MWCNT-HA/Cu-H3BTC nanocomposite, Journal of Industrial and Engineering Chemistry 114 (2022) 418-426. https://doi.org/10.1016/j.jiec.2022.07.032

R.M. Mohabis, F. Fazeli, I. Amini, V. Azizkhani, An overview of recent advances in the detection of ascorbic acid by electrochemical techniques, Journal of Electrochemical Science and Engineering 12 (2022) 1081-1098. https://doi.org/10.5599/jese.1561

H. Medetalibeyoğlu, An investigation on development of a molecular imprinted sensor with graphitic carbon nitride (g-C3N4) quantum dots for detection of acetaminophen, Carbon Letters 31 (2021) 1237-1248. https://doi.org/10.1007/s42823-021-00247-0

G. Li, J. Li, Z. Yang, An electrochemical sensor based on graphene-chitosan-cyclodextrin modification for the detection of Staphylococcus aureus, Carbon Letters (2023) https://doi.org/10.1007/s42823-023-00518-y

S. Ariavand, M. Ebrahimi, E. Foladi, Design and construction of a novel and an efficient potentiometric sensor for determination of sodium ion in urban water samples, Chemical Methodologies 6 (2022) 886-904. https://doi.org/10.22034/chemm.2022.348712.1567

A.R. Umar, K. Hussain, Z. Aslam, M.A.U. Haq, H. Muhammad, M.R. Shah, Ultra-trace level voltammetric sensor for MB in human plasma based on a carboxylic derivative of Calix [4] resorcinarene capped silver nanoparticles, Journal of Industrial and Engineering Chemistry 107 (2022) 81-92. https://doi.org/10.1016/j.jiec.2021.11.024

B. Muthukutty, J. Ganesamurthi, T.-W. Chen, S.-M. Chen, J. Yu, X. Liu, A novel high-performance electrocatalytic determination platform for voltammetric sensing of eugenol in acidic media using pyrochlore structured lanthanum stannate nanoparticles, Journal of Industrial and Engineering Chemistry 106 (2022) 103-112. https://doi.org/10.1016/j.jiec.2021.10.015

B.B. Mulik, A.V. Munde, R.P. Dighole, B.R. Sathe, Electrochemical determination of semicarbazide on cobalt oxide nanoparticles: Implication towards environmental monitoring, Journal of Industrial and Engineering Chemistry 93 (2021) 259-266. https://doi.org/10.1016/j.jiec.2020.10.002

A.R. Cherian, L. Benny, A. George, A. Varghese, G. Hegde, Recent advances in functionalization of carbon nanosurface structures for electrochemical sensing applications: tuning and turning, Journal of Nanostructure in Chemistry 12 (2021) 441-466. https://doi.org/10.1007/s40097-021-00426-5

A. John, L. Benny, A.R. Cherian, S.Y. Narahari, A. Varghese, G. Hegde, Electrochemical sensors using conducting polymer/noble metal nanoparticle nanocomposites for the detection of various analytes: a review, Journal of Nanostructure in Chemistry 11 (2021) 1-31. https://doi.org/10.1007/s40097-020-00372-8

B. Davarnia, S.-A. Shahidi, H. Karimi-Maleh, A. Ghorbani-HasanSaraei, F. Karimi, Biosynthesis of Ag nanoparticle by peganum harmala extract; antimicrobial activity and ability for fabrication of quercetin food electrochemical sensor, International Journal of Electrochemical Science 15 (2020) 2549-2560. https://doi.org/10.20964/2020.03.70

H. Karimi-Maleh, R. Darabi, M. Baghayeri, F. Karimi, L. Fu, J. Rouhi, D.E. Niculina, E.S. Gündüz, E. Dragoi, Recent developments in carbon nanomaterials-based electrochemical sensors for methyl parathion detection, Journal of Food Measurement and Characterization 17 (2023) 5371-5389. https://doi.org/10.1007/s11694-023-02050-z

P. Ebrahimi, S.-A. Shahidi, M. Bijad, A rapid voltammetric strategy for determination of ferulic acid using electrochemical nanostructure tool in food samples, Journal of Food Measurement and Characterization 14 (2020) 3389-3396. https://doi.org/10.1007/s11694-020-00585-z

H. Sadeghi, S.-A. Shahidi, S.N. Raeisi, A. Ghorbani-HasanSaraei, F. Karimi, Electrochemical determination of vitamin B6 in water and juice samples using an electrochemical sensor amplified with NiO/CNTs and Ionic liquid, International Journal of Electrochemical Science 15 (2020) 10488-10498. https://doi.org/10.20964/2020.10.51

F. Karimi, E. Demir, N. Aydogdu, M. Shojaei, M.A. Taher, P.N. Asrami, M. Alizadeh, Y. Ghasemi, S. Cheraghi, Advancement in electrochemical strategies for quantification of Brown HT and Carmoisine (Acid Red 14) From Azo Dyestuff class, Food and Chemical Toxicology 165 (2022) 113075. https://doi.org/10.1016/j.fct.2022.113075

M. Alizadeh, E. Demir, N. Aydogdu, N. Zare, F. Karimi, S.M. Kandomal, H. Rokni, Y. Ghasemi, Recent advantages in electrochemical monitoring for the analysis of amaranth and carminic acid food colors, Food and Chemical Toxicology 163 (2022) 112929. https://doi.org/10.1016/j.fct.2022.112929

A. L. Branen, P. M. Davidson, S. Salminen, J. Thorngate, Food Additives, CRC Press, 2001. https://doi.org/10.1201/9780367800505

G. Van Esch, Toxicology of tert-butylhydroquinone (TBHQ), Food and Chemical Toxicology 24 (1986) 1063-1065. https://doi.org/10.1016/0278-6915(86)90289-9

W. Cao, Y. Wang, Q. Zhuang, L. Wang, Y. Ni, Developing an electrochemical sensor for the detection of tert-butylhydroquinone, Sensors and Actuators B 293 (2019) 321-328. https://doi.org/10.1016/j.snb.2019.05.012

Y. Pan, K. Lai, Y. Fan, C. Li, L. Pei, B.A. Rasco, Y. Huang, Determination of tert‐butylhydroquinone in vegetable oils using surface‐enhanced Raman spectroscopy, Journal of Food Science 79 (2014) T1225-T1230. https://doi.org/10.1111/1750-3841.12482

S.S. Siwal, A.K. Saini, S. Rarotra, Q. Zhang, V.K. Thakur, Recent advancements in transparent carbon nanotube films: chemistry and imminent challenges, Journal of Nanostructure in Chemistry 11 (2021) 93-130. https://doi.org/10.1007/s40097-020-00378-2

A. Mohammadnavaz, F. Garkani-Nejad, Voltammetric determination of hydrochlorothiazide at a modified carbon paste electrode with polypyrrole nanotubes, ADMET and DMPK 11 (2023) 293-302. https://doi.org/10.5599/admet.1706

A. Hosseinian-Roudsari, S.-A. Shahidi, A. Ghorbani-HasanSaraei, S. Hosseini, F. Fazeli, A new electroanalytical approach for sunset yellow monitoring in fruit juices based on a modified sensor amplified with nanocatalyst and ionic liquid, Food and Chemical Toxicology 168 (2022) 113362. https://doi.org/10.1016/j.fct.2022.113362

S. Salmanpour, A. Sadrnia, F. Karimi, N. Majani, M.L. Yola, V.K. Gupta, NiO nanoparticle decorated on single-wall carbon nanotubes and 1-butyl-4-methylpyridinium tetrafluoroborate for sensitive raloxifene sensor, Journal of Molecular Liquids 254 (2018) 255-259. https://doi.org/10.1016/j.molliq.2018.01.105

Q. Zhao, Z. Gan, Q. Zhuang, Electrochemical sensors based on carbon nanotubes, Electroanalysis 14 (2002) 1609-1613. https://doi.org/10.1002/elan.200290000

A. Ambika, N. Navya, S. Kiran Kumar, B. Suresha, Electrochemical determination of paracetamol by SWCNT-modified carbon paste electrode: a cyclic voltammetric study, Carbon Letters 32 (2022) 1287-1295. https://doi.org/10.1007/s42823-022-00354-6

S. Zheng, J. Fan, F. Yin, J. Chen, Z. Hui, J. Tang, X. Wang, J. Guo, Electrochemical determination of tert-butylhydroquinone by ZIF-67@ TiO2 derived hierarchical TiO 2/Co/NCNTs, New Journal of Chemistry 47(33) (2023) 15569-15578. https://doi.org/10.1039/D3NJ02149A

M.-H. Karimi-Harandi, M. Shabani-Nooshabadi, R. Darabi, Cu-BTC metal-organic frameworks as catalytic modifier for ultrasensitive electrochemical determination of methocarbamol in the presence of methadone, Journal of The Electrochemical Society 168 (2021) 097507. https://doi.org/10.1149/1945-7111/ac2468



10-10-2023 — Updated on 11-10-2023

How to Cite

Dehdashtian, N., Shahidi, S.-A., Ghorbani-HasanSaraei, A., Hosseini, S., & Ahmadi, M. (2023). Electroanalysis of tert-butylhydroquinone in food products using a paste electrode enlarged with single wall carbon nanotubes as catalyst: Original scientific paper. Journal of Electrochemical Science and Engineering, 14(1), 37–45. https://doi.org/10.5599/jese.2016



Electroanalytical chemistry