Electrochemical determination of tramadol using modified screen printed electrode

Original scientific paper


  • Sayed Zia Mohammadi Department of Chemistry, Payame Noor University, Tehran, Iran https://orcid.org/0000-0001-6980-9121
  • Maedeh Jafari Department of Pediatrics, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran
  • Peyman Mohammadzadeh Jahani Student Research Committee, School of Public Health, Bam University of Medical Sciences, Bam, Iran
  • Sayed Ali Ahmadi Department of Chemistry, Kerman Branch, Islamic Azad University, Kerman, Iran. https://orcid.org/0000-0002-0880-5765
  • Raana Mashayekh Student Research Committee, Bam University of Medical Sciences, Bam, Iran




La3 /ZnO nano-flower, multi-walled carbon nanotubes, voltammetry
Graphical Abstract


The detection of tramadol using a screen printed electrode modified with La3+/ZnO nano-flowers and multi-walled carbon nanotubes (La3+/ZnO NFs-MWCNTs/SPE) is reported in this work. In order to examine tramadol electrochemical oxidation, the modified electrode was implemented with the utilization of differential pulse voltammetry, chronoamperometry and cyclic voltammetry as diagnostic techniques. The proposed electrode displays favorable electrocatalytic behavior concerning tramadol oxidation with an approximately 330 mV potential shift to a lesser positive potential. In the 0.5 to 800.0 μM range for tramadol, differential pulse voltammetry displays linear dynamic activity. Tramadol detection limit of 0.08 μM was derived within optimized testing conditions for this simple construction sensor. Lastly, this fabricated sensor was utilized with desirable results to determine tramadol in tramadol samples and urine samples.


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How to Cite

Mohammadi, S. Z., Jafari, M. ., Mohammadzadeh Jahani, P. . . ., Ahmadi, S. A., & Mashayekh, R. . (2021). Electrochemical determination of tramadol using modified screen printed electrode: Original scientific paper. Journal of Electrochemical Science and Engineering, 12(1), 127–135. https://doi.org/10.5599/jese.1141



Electrochemical Science

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