A WSe2@poly(3,4-ethylenedioxythiophene) nanocomposite-based electrochemical sensor for simultaneous detection of dopamine and uric acid

Original scientific paper


  • Yasin Tangal Burdur Mehmet Akif Ersoy University, The Graduate School of Natural and Applied Sciences, Department of Chemistry, 15030, Burdur, Turkey https://orcid.org/0000-0003-4929-3767
  • Deniz Coban Burdur Mehmet Akif Ersoy University, The Graduate School of Natural and Applied Sciences, Department of Material Technology Engineering, 15030, Burdur, Turkey https://orcid.org/0000-0003-0798-798X
  • Sadik Cogal Burdur Mehmet Akif Ersoy University, Faculty of Arts and Science, Department of Chemistry, 15030, Burdur, Turkey https://orcid.org/0000-0001-8904-1332




Tungsten diselenide, modified electrode, conducting polymer, selective sensing, biological compounds


In the present work, a nanocomposite of two-dimensional WSe2 nanosheets with poly-
(3,4‑ethylenedioxythiophene (WSe2@PEDOT) was prepared by facile hydrothermal method and characterized in terms of structural and morphological analyses. This nano­composite was used to modify glassy carbon electrode for the construction of an electrochemical sen­sing platform for simultaneous determination of dopamine (DA) and uric acid (UA) in the presence of ascorbic acid (AA). It was found that the incorporation of PEDOT into WSe2 nano­sheets exhibited enhanced electrochemical behaviors and electro¬catalytic activity against DA and UA. Using differential pulse voltammetry (DPV) measurements, the WSe2@PEDOT modified electrode displayed wide linear detection ranges of 16 to 466 µM for DA and 20 to 582.5 µM for UA. The electrode also exhibited high selectivity against DA and UA in the presence of major interference of ascorbic acid and other interferent substances.


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Electrochemical Science