ADMET and DMPK

Vol 7, No 1 (2019)

Physiologically based pharmacokinetic (PBPK) modeling and simulation in drug discovery and development

Guest editors: Abdul Naveed Shaik and Ansar Ali Khan

Table of Contents

Editorial

Physiologically based pharmacokinetic (PBPK) modeling and simulation in drug discovery and development PDF
Abdul Naveed Shaik, Ansar Ali Khan 1-3

Original Scientific Articles

Building in-house PBPK modelling tools for oral drug administration from literature information Supplementary material PDF
Silvia Grandoni, Nicola Cesari, Giandomenico Brogin, Paola Puccini, Paolo Magni 4-21
A physiologically-based pharmacokinetic model of oseltamivir phosphate and its carboxylate metabolite for rats and humans PDF
Guanghua Gao, Francis Law, Ricky Ngok Shun Wong, Nai Ki Mak, Mildred Sze Ming Yang 22-43
Physiologically-based pharmacokinetic simulations in pharmacotherapy: selection of the optimal administration route for exogenous melatonin PDF
Adriana Savoca, Davide Manca 44-59
PKQuest: PBPK modeling of highly lipid soluble and extracellular solutes PDF
David G. Levitt 60-75
Nicotinic acid in nanocontainers. Encapsulation and release from ion exchangers PDF
Heinrich Altshuler, Elena Ostapova, Olga Altshuler, Galina Shkurenko, Natalya Malyshenko, Sergey Lyrschikov, Roman Parshkov 76-87


ISSN 1848-7718