Vol 3, No 1 (2015)

Transporters and permeability

Guest editor: Kiyohiko Sugano

Table of Contents


The extended clearance model and its use for the interpretation of hepatobiliary elimination data PDF
Gian Camenisch, Julia Riede, Annett Kunze, Jörg Huwyler, Birk Poller, Kenichi Umehara 1-14

Original Scientific Articles

Expression and Transport of a-Synuclein at the Blood-Cerebrospinal Fluid Barrier and Effects of Manganese Exposure PDF
Christopher A Bates, Sherleen Fu, Daniel Ysselstein, Jean-Christophe Rochet, Wei Zheng 15-33
Characterization of SLC transporters in human skin PDF
Marion Alriquet, Karine Sevin, Alexandre Gaborit, Pierre Comby, Bernard Ruty, Hanan Osman-Ponchet 34-44
Effect of Bioenhancers on Amoxicillin bioavailability PDF
Kalyani Barve, Kushal Ruparel 45-50
Adaptation of a human gut epithelial model in relation to the assessment of clinical pharmacokinetic parameters for selected tyrosine kinase inhibitors PDF
Richard Honeywell, Christien Fatmawati, Marita Buddha, Sarina Hitzerd, Ietje Kathman, Godefridus Peters 51-67

Short Communications

P-glycoprotein-dependent pharmacokinetics of irinotecan and its active metabolite, SN-38 in rats: Effect of verapamil PDF
Tripta Garg, Manu Jaggi, Roop K. Khar, Sushama Talegaonkar 68-76


Differential effects of mitogen-activated protein kinase pathway inhibitors on P-glycoprotein activation PDF
Hirokazu Wakuda, Shino Miyauchi, Kana Maruyama, Satomi Kagota, Kazuki Nakamura, Keizo Umegaki, Shizuo Yamada, Kazumasa Shinozuka 77-83

ISSN 1848-7718