J. Electrochem. Sci. Eng.  

Application of Fe3O4@SiO2/GO nanocomposite for sensitive and selective electrochemical sensing of tryptophan

Hadi Beitollahi, Mohadeseh Safaei, Masoud Reza Shishehbore, Somayeh Tajik


A simple strategy for determination of tryptophan (TRP) based on Fe3O4@SiO2/GO nano­composite modified graphite screen printed electrode (Fe3O4@SiO2/GO/SPE) is re­ported. Cyclic voltammetry (CV) and differential pulse voltammetry (DPV) were used to characterize the performance of the sensor. The Fe3O4@SiO2/GO/SPE displayed excellent electro­che­mical catalytic activities. The oxidation overpotentials of tryptophan decreased significantly and its oxidation peak current increased dramatically at Fe3O4@SiO2/GO/SPE. Under the optimized experimental conditions tryptophan showed linear response over the range of 1.0-400.0 μM. The lower detection limit was found to be 0.2 μM for tryptophan. The prac­tical application of the modified electrode was demonstrated by measuring the concen­tration of tryptophan in real samples.


Tryptophan; Fe3O4@SiO2/GO nanocomposite; graphite screen printed electrodes; voltammetry

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DOI: http://dx.doi.org/10.5599/jese.576

jESE : : Open Access Journal  :  : ISSN 1847-9286